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MERCK SHARP & DOHME

US1,534 patents

Top patents by PatentIndex Score

US6214846B1Apr 10, 2001

Substituted 3-(benzylamino)piperidine derivatives and their use as therapeutic agents

MERCK SHARP & DOHME85 citations98
US5514718AMay 7, 1996

Heterocyclic compounds, processes for their preparation and pharmaceutical compositions containing them

MERCK SHARP & DOHME551 citations98
USD870270SDec 17, 2019

Autoinjector pen

MERCK SHARP & DOHME48 citations97
USD857192SAug 20, 2019

Autoinjector device

MERCK SHARP & DOHME75 citations97
US10188730B2Jan 29, 2019

Anti-LAG3 antibodies and antigen-binding fragments

MERCK SHARP & DOHME42 citations97
US10106574B2Oct 23, 2018

Cyclic di-nucleotide compounds as sting agonists

MERCK SHARP & DOHME34 citations97
USD793547SAug 1, 2017

Autoinjector pen

MERCK SHARP & DOHME65 citations97
USD780909SMar 7, 2017

Autoinjector pen

MERCK SHARP & DOHME104 citations97
US7951797B2May 31, 2011

Substituted diazepan orexin receptor antagonists

MERCK SHARP & DOHME59 citations97
US7176203B2Feb 13, 2007

Imidazo-triazine derivatives as ligands for gaba receptors

MERCK SHARP & DOHME63 citations97
US6479480B1Nov 12, 2002

Phenylindole derivatives as 5-ht2a receptor ligands

MERCK SHARP & DOHME89 citations97
US6172077B1Jan 9, 2001

Spiro-azacyclic derivatives and their use as therapeutic agents

MERCK SHARP & DOHME149 citations97
US5885999AMar 23, 1999

Serine derivatives and their use as therapeutic agents

MERCK SHARP & DOHME103 citations97
US5298520AMar 29, 1994

Triazole containing indole derivatives

MERCK SHARP & DOHME97 citations97
US10189831B2Jan 29, 2019

Non-nucleoside reverse transcriptase inhibitors

MERCK SHARP & DOHME75 citations96
US8952136B2Feb 10, 2015

Antibodies to human programmed death receptor PD-1

MERCK SHARP & DOHME174 citations96
US8900587B2Dec 2, 2014

Antibodies to human programmed death receptor PD-1

MERCK SHARP & DOHME411 citations96
US7973040B2Jul 5, 2011

Macrocyclic quinoxaline compounds as HCV NS3 protease inhibitors

MERCK SHARP & DOHME40 citations96
US7879815B2Feb 1, 2011

Nucleoside aryl phosphoramidates for the treatment of RNA-dependent RNA viral infection

MERCK SHARP & DOHME132 citations96
US6756511B2Jun 29, 2004

Gamma-secretase inhibitors

MERCK SHARP & DOHME83 citations96
US6448229B2Sep 10, 2002

Gamma secretase inhibitors

MERCK SHARP & DOHME54 citations96
US6136824AOct 24, 2000

1-piperidinyl-propan-2-derivatives and their use as therapeutic agents

MERCK SHARP & DOHME61 citations96
US5714498AFeb 3, 1998

Benzimidazole derivatives

MERCK SHARP & DOHME61 citations96
US5614518AMar 25, 1997

Morpholine derivatives as dopamine receptor subtype ligands

MERCK SHARP & DOHME66 citations96
US5614532AMar 25, 1997

Quinolone derivatives

MERCK SHARP & DOHME75 citations96
US5459270AOct 17, 1995

Azacyclic compounds, processes for their preparation and pharmaceutical compositions containing them

MERCK SHARP & DOHME69 citations96
US5451588ASep 19, 1995

Imidazole, triazole and tetrazole derivatives

MERCK SHARP & DOHME39 citations96
USD774641SDec 20, 2016

Auto injector

MERCK SHARP & DOHME89 citations95
US5880132AMar 9, 1999

Tachykinin antagonist and an opioid analgesic effective at treating pain or nociception

MERCK SHARP & DOHME132 citations95
US5556969ASep 17, 1996

Benzodiazepine derivatives

MERCK SHARP & DOHME94 citations95
US5317103AMay 31, 1994

Indole-substituted five-membered heteroaromatic compounds as 5-HT1 agonists

MERCK SHARP & DOHME63 citations95
US5106853AApr 21, 1992

Oxadiazole and its salts, their use in treating dementia

MERCK SHARP & DOHME77 citations95
US4377568AMar 22, 1983

Preparation of aqueous alcoholic dispersions of pH sensitive polymers and plasticizing agents and a method of enteric coating dosage forms using same

MERCK SHARP & DOHME155 citations95
US9624197B2Apr 18, 2017

2-pyridylamino-4-nitrile-piperidinyl orexin receptor antagonists

MERCK SHARP & DOHME24 citations94
US9586934B2Mar 7, 2017

2-pyridyloxy-4-methyl orexin receptor antagonists

MERCK SHARP & DOHME25 citations94
US9156819B2Oct 13, 2015

2-pyridyloxy-4-nitrile orexin receptor antagonists

MERCK SHARP & DOHME34 citations94
US8344114B2Jan 1, 2013

Antagonists of PCSK9

MERCK SHARP & DOHME58 citations94
US7951795B2May 31, 2011

Constrained spirocyclic compounds as CGRP receptor antagonists

MERCK SHARP & DOHME43 citations94
US6486153B1Nov 26, 2002

Phenylindole derivatives as 5-HT2A receptor ligands

MERCK SHARP & DOHME57 citations94
US6476030B1Nov 5, 2002

Pyrazolo-triazine derivatives as ligands for GABA receptors

MERCK SHARP & DOHME70 citations94
US5620989AApr 15, 1997

4-Arylmethyloxymethyl piperidines as tachykinin antagonsits

MERCK SHARP & DOHME61 citations94
US5494926AFeb 27, 1996

2/3-(heterocyclic alkyl amino)-1-(subst.-phenyl-methoxy)-ethanes/propanes as tachykinin-receptor antagonists

MERCK SHARP & DOHME67 citations94
US5242930ASep 7, 1993

Azabicyclic compounds, pharmaceutical compositions containing them and their use in therapy

MERCK SHARP & DOHME73 citations94
US5219860AJun 15, 1993

Spirocyclic antipsychotic agents

MERCK SHARP & DOHME54 citations94
US10544222B2Jan 28, 2020

PD1/CTLA4 binders

MERCK SHARP & DOHME22 citations93
US10501542B2Dec 10, 2019

CTLA4 binders

MERCK SHARP & DOHME16 citations93
US10323090B2Jun 18, 2019

PD1 and/or LAG3 binders

MERCK SHARP & DOHME26 citations93
US10272077B2Apr 30, 2019

Piperidinone carboxamide azaindane CGRP receptor antagonists

MERCK SHARP & DOHME16 citations93
US9718818B2Aug 1, 2017

Compounds inhibiting leucine-rich repeat kinase enzyme activity

MERCK SHARP & DOHME25 citations93
USD777907SJan 31, 2017

Medical injector pen

MERCK SHARP & DOHME23 citations93

Showing the top 50 of 1,534 patents by PatentIndex Score.