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ALNYLAM PHARMACEUTICALS INC

US341 patents

Top patents by PatentIndex Score

US9796974B2Oct 24, 2017

Modified RNAi agents

ALNYLAM PHARMACEUTICALS INC119 citations99
US8828956B2Sep 9, 2014

Carbohydrate conjugates as delivery agents for oligonucleotides

ALNYLAM PHARMACEUTICALS INC224 citations99
US8344125B2Jan 1, 2013

Modified iRNA agents

ALNYLAM PHARMACEUTICALS INC103 citations99
US7749978B2Jul 6, 2010

Compositions and methods for inhibiting expression of Huntingtin gene

ALNYLAM PHARMACEUTICALS INC113 citations99
US7745608B2Jun 29, 2010

Modified iRNA agents

ALNYLAM PHARMACEUTICALS INC129 citations99
US7718629B2May 18, 2010

Compositions and methods for inhibiting expression of Eg5 gene

ALNYLAM PHARMACEUTICALS INC241 citations99
US7605251B2Oct 20, 2009

Compositions and methods for inhibiting expression of the PCSK9 gene

ALNYLAM PHARMACEUTICALS INC160 citations99
US7582744B2Sep 1, 2009

Chemically modified oligonucleotides

ALNYLAM PHARMACEUTICALS INC177 citations99
US7423142B2Sep 9, 2008

Compositions and methods for inhibiting expression of anti-apoptotic genes

ALNYLAM PHARMACEUTICALS INC118 citations99
US7320965B2Jan 22, 2008

Compositions and methods for inhibiting expression of Huntingtin gene

ALNYLAM PHARMACEUTICALS INC208 citations99
US11246933B1Feb 15, 2022

Biodegradable lipids for the delivery of active agents

ALNYLAM PHARMACEUTICALS INC30 citations98
US10369226B2Aug 6, 2019

Biodegradable lipids for the delivery of active agents

ALNYLAM PHARMACEUTICALS INC25 citations98
US10337010B2Jul 2, 2019

Angiopoietin-like 3 (ANGPTL3) iRNA compositions and methods of use thereof

ALNYLAM PHARMACEUTICALS INC17 citations98
US9771591B2Sep 26, 2017

Angiopoietin-like 3 (ANGPTL3) iRNA compositions and methods of use thereof

ALNYLAM PHARMACEUTICALS INC22 citations98
US9399775B2Jul 26, 2016

RNAi agents, compositions and methods of use thereof for treating transthyretin (TTR) associated diseases

ALNYLAM PHARMACEUTICALS INC51 citations98
US9352048B2May 31, 2016

Carbohydrate conjugates as delivery agents for oligonucleotides

ALNYLAM PHARMACEUTICALS INC112 citations98
US9322018B2Apr 26, 2016

Angiopoietin-like 3 (ANGPTL3) iRNA compositions and methods of use thereof

ALNYLAM PHARMACEUTICALS INC36 citations98
US9061063B2Jun 23, 2015

Biodegradable lipids for the delivery of active agents

ALNYLAM PHARMACEUTICALS INC41 citations98
US8809516B2Aug 19, 2014

Therapeutic compositions

ALNYLAM PHARMACEUTICALS INC43 citations98
US7737265B2Jun 15, 2010

RNAi modulation of HIF-1 and therapeutic uses thereof

ALNYLAM PHARMACEUTICALS INC122 citations98
US7582745B2Sep 1, 2009

Compositions and methods for inhibiting expression of Nav1.8 gene

ALNYLAM PHARMACEUTICALS INC152 citations98
US10612027B2Apr 7, 2020

Modified double-stranded RNA agents

ALNYLAM PHARMACEUTICALS INC26 citations97
US10233448B2Mar 19, 2019

Modified double-stranded RNA agents

ALNYLAM PHARMACEUTICALS INC37 citations97
US9867882B2Jan 16, 2018

Carbohydrate conjugates as delivery agents for oligonucleotides

ALNYLAM PHARMACEUTICALS INC33 citations97
US9370581B2Jun 21, 2016

Carbohydrate conjugates as delivery agents for oligonucleotides

ALNYLAM PHARMACEUTICALS INC24 citations97
US7829693B2Nov 9, 2010

Compositions and methods for inhibiting expression of a target gene

ALNYLAM PHARMACEUTICALS INC134 citations97
US9370582B2Jun 21, 2016

Carbohydrate conjugates as delivery agents for oligonucleotides

ALNYLAM PHARMACEUTICALS INC23 citations96
US7851615B2Dec 14, 2010

Lipophilic conjugated iRNA agents

ALNYLAM PHARMACEUTICALS INC103 citations96
US7786290B2Aug 31, 2010

Double-stranded ribonucleic acid with increased effectiveness in an organism

ALNYLAM PHARMACEUTICALS INC99 citations96
US7517865B2Apr 14, 2009

RNAi modulation of RSV and therapeutic uses thereof

ALNYLAM PHARMACEUTICALS INC38 citations96
US11679158B2Jun 20, 2023

Biodegradable lipids for the delivery of active agents

ALNYLAM PHARMACEUTICALS INC7 citations94
US11633479B2Apr 25, 2023

Biodegradable lipids for the delivery of active agents

ALNYLAM PHARMACEUTICALS INC11 citations94
US11633480B2Apr 25, 2023

Biodegradable lipids for the delivery of active agents

ALNYLAM PHARMACEUTICALS INC11 citations94
US11612657B2Mar 28, 2023

Biodegradable lipids for the delivery of active agents

ALNYLAM PHARMACEUTICALS INC9 citations94
US11590229B2Feb 28, 2023

Biodegradable lipids for the delivery of active agents

ALNYLAM PHARMACEUTICALS INC11 citations94
US11525138B2Dec 13, 2022

Angiopoietin-like 3 (ANGPTL3) iRNA compositions and methods of use thereof

ALNYLAM PHARMACEUTICALS INC7 citations94
US11382979B2Jul 12, 2022

Biodegradable lipids for the delivery of active agents

ALNYLAM PHARMACEUTICALS INC18 citations94
US11332743B2May 17, 2022

Angiopoietin-like 3 (ANGPTL3) iRNA compositions and methods of use thereof

ALNYLAM PHARMACEUTICALS INC6 citations94
US11306315B2Apr 19, 2022

Angiopoietin-like 3 (ANGPTL3) iRNA compositions and methods of use thereof

ALNYLAM PHARMACEUTICALS INC6 citations94
US11306316B2Apr 19, 2022

Angiopoietin-like 3 (ANGPTL3) iRNA compositions and methods of use thereof

ALNYLAM PHARMACEUTICALS INC6 citations94
US11306314B2Apr 19, 2022

Angiopoietin-like 3 (ANGPTL3) iRNA compositions and methods of use thereof

ALNYLAM PHARMACEUTICALS INC6 citations94
US11110174B2Sep 7, 2021

Carbohydrate conjugates as delivery agents for oligonucleotides

ALNYLAM PHARMACEUTICALS INC10 citations94
US10934544B2Mar 2, 2021

Factor XII (hageman factor) (F12), kallikrein B, plasma (fletcher factor) 1 (KLKB1), and kininogen 1 (KNG1) iRNA compositions and methods of use thereof

ALNYLAM PHARMACEUTICALS INC15 citations94
US10806791B2Oct 20, 2020

Carbohydrate conjugates as delivery agents for oligonucleotides

ALNYLAM PHARMACEUTICALS INC14 citations94
US10668170B2Jun 2, 2020

Modified RNAi agents

ALNYLAM PHARMACEUTICALS INC22 citations94
US10570393B2Feb 25, 2020

Angiopoietin-like 3 (ANGPTL3) iRNA compositions and methods of use thereof

ALNYLAM PHARMACEUTICALS INC17 citations94
US10557139B2Feb 11, 2020

Angiopoietin-like 3 (ANGPTL3) iRNA compositions and methods of use thereof

ALNYLAM PHARMACEUTICALS INC15 citations94
US10550390B2Feb 4, 2020

Angiopoietin-like 3 (ANGPTL3) iRNA compositions and methods of use thereof

ALNYLAM PHARMACEUTICALS INC15 citations94
US9708607B2Jul 18, 2017

Modified RNAi agents

ALNYLAM PHARMACEUTICALS INC41 citations94
US9682922B2Jun 20, 2017

Biodegradable lipids for the delivery of active agents

ALNYLAM PHARMACEUTICALS INC39 citations94

Showing the top 50 of 341 patents by PatentIndex Score.