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ALNYLAM PHARMACEUTICALS
US6 patents
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US7723509B2May 25, 2010
IRNA agents with biocleavable tethers
ALNYLAM PHARMACEUTICALS202 citations99
US7626014B2Dec 1, 2009
Single-stranded and double-stranded oligonucleotides comprising a 2-arylpropyl moiety
ALNYLAM PHARMACEUTICALS53 citations97
US9127274B2Sep 8, 2015
Serpinc1 iRNA compositions and methods of use thereof
ALNYLAM PHARMACEUTICALS51 citations96
US7772387B2Aug 10, 2010
Oligonucleotides comprising a modified or non-natural nucleobase
ALNYLAM PHARMACEUTICALS22 citations92
US7723512B2May 25, 2010
Oligonucleotides comprising a non-phosphate backbone linkage
ALNYLAM PHARMACEUTICALS26 citations92
US7674778B2Mar 9, 2010
Oligonucleotides comprising a conjugate group linked through a C5-modified pyrimidine
ALNYLAM PHARMACEUTICALS7 citations63