Compositions and kits useful for treatment of respiratory illness

Abstract

The invention relates to a clear device: comprising a composition contained in a device; wherein said composition comprising a pharmaceutical active selected from the group consisting of phenylephrine, its free and addition salt forms, and mixtures thereof. Also disclosed are kits comprising: a composition contained in a device; wherein said composition comprising a pharmaceutical active selected from the group consisting of phenylephrine, its free and addition salt forms, and mixtures thereof.

1 . A clear device: comprising a composition contained in a device; wherein said composition comprising a pharmaceutical active selected from the group consisting of phenylephrine, its free and addition salt forms, and mixtures thereof; and wherein said device comprises a material selected from the group consisting of Polyethylene Terephthalate (PET), Glycol-modified Polyethylene Terephthalate (PETG), Oriented Polypropylene (OPP), Polyvinylchloride (PVC), Polyvinylidene Chloride (PVDC), Nylon, Polyethylene Terphthalate Polyester (PETP), Polyphene, and combinations thereof. 
   
   
       2 . The clear device of  claim 1 , wherein said material is Polyethylene Terephthalate (PET). 
   
   
       3 . The clear device of  claim 1 , wherein said composition has a pH of from about 2 to about 6.5. 
   
   
       4 . The clear device of  claim 1 , wherein said composition has a pH of from about 2 to about 5. 
   
   
       5 . The clear device of  claim 1 , comprising from about 0.0001% to about 2% pharmaceutical active, by weight of the composition. 
   
   
       6 . The clear device of  claim 1 , wherein said composition further comprising a sweetener. 
   
   
       7 . The clear device of  claim 6 , wherein said sweetener comprises an artificial sweetener. 
   
   
       8 . The clear device of  claim 7 , wherein said artificial sweetener is selected from the group consisting of: sodium saccharin, acesulfame potassium, sucralose, aspartame, monoammonium glycyrrhizinate, neohesperidin dihydrochalcone, thaumatin, neotame, cyclamates, and mixtures thereof. 
   
   
       9 . The clear device of  claim 8 , comprising from about 0.0001% to about 1% of said artificial sweetener, by weight of said composition. 
   
   
       10 . The clear device of  claim 1 , wherein said composition further comprising at least one additional pharmaceutical active. 
   
   
       11 . The clear device of  claim 10 , wherein said additional pharmaceutical active is selected from the group consisting of antitussives, antihistamines, non-sedating antihistamines, decongestants, expectorants, analgesics, antipyretic anti-inflammatory agents, local anesthetics, anti-inflammatory agents, demulcents, herbal remedies, vitamins, supplements, antioxidants, natural ingredients, minerals, energy boosting ingredients, sleep aids and immune system boosting ingredients, and mixtures thereof. 
   
   
       12 . The clear device of  claim 1 , wherein said composition further comprising a chelating agent. 
   
   
       13 . The clear device of  claim 12 , wherein said chelating agent is selected from the group consisting of: ethylene diamine tetraacetic acid (EDTA), tetrasodium EDTA, sodium hexametaphosphate (SHMP), citric acid, phosphoric acid, di(hydroxyethyl)glycine, 8-hydroxyquinoline, salts thereof and mixtures thereof. 
   
   
       14 . The clear device of  claim 12 , comprising from about 0.0001% to about 2% of said chelating agent, by weight of said composition. 
   
   
       15 . The clear device of  claim 1 , wherein said composition further comprising an additional ingredient selected from the group consisting of a solvent, a reducing agent. a non-aldehydic aesthetic agent, a chloride salt, a coolant, a colorant, a preservative, a fragrance, and combinations thereof. 
   
   
       16 . The clear device of  claim 1 , wherein said device delivers from about 5 ml to about 50 ml of said composition per dose. 
   
   
       17 . The clear device of  claim 16 , wherein said composition is administered at least once daily. 
   
   
       18 . A kit comprising: a composition contained in a device; wherein said composition comprising a pharmaceutical active selected from the group consisting of phenylephrine, its free and addition salt forms, and mixtures thereof; and wherein said device comprises a material selected from the group consisting of Polyethylene Terephthalate (PET), Glycol-modified Polyethylene Terephthalate (PETG), Oriented Polypropylene (OPP), Polyvinylchloride (PVC), Polyvinylidene Chloride (PVDC), Nylon, Polyethylene Terphthalate Polyester (PETP), Polyphene, and combinations thereof. 
   
   
       19 . The kit of  claim 18 , further comprising a set of instructions. 
   
   
       20 . The kit of  claim 18 , wherein said composition further comprising at least one additional pharmaceutical active. 
   
   
       21 . The kit of  claim 18 , wherein said kit further comprising at least one additional pharmaceutical active.