US2004242524A1PendingUtilityA1

Chemotherapeutic composition and method

Priority: Dec 4, 1998Filed: Mar 23, 2004Published: Dec 2, 2004

Est. expiryDec 4, 2018(expired)· nominal 20-yr term from priority

Inventors:Nigel C. Phillips Mario Filion

A61K 45/06

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Abstract

The present invention relates to a composition and method comprising Mycobacterium phlei ( M. phlei )-DNA (M-DNA), M-DNA preserved and complexed on M. phlei cell wall (MCC), a chemotherapeutic agent and a pharmaceutically acceptable carrier, wherein the M-DNA and the MCC induce cell cycle arrest in proliferating cancer cells, inhibit proliferation of cancer cells, induce apoptosis in cancer cells and potentiate the antineoplastic effect of the chemotherapeutic agent on cancer cells.

Claims

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1 - 16 . (Cancelled)  
     
     
         17 . A composition comprising M-DNA and a chemotherapeutic agent, wherein the M-DNA potentiates the anti-cancer activity of the chemotherapeutic agent in treating cancer in an animal having cancer.  
     
     
         18 . A composition comprising MCC and a chemotherapeutic agent, wherein the MCC potentiates the anti-cancer activity of the chemotherapeutic agent in treating cancer in an animal having cancer.

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