Inventor · disambiguated record
Larry K. Keefer
Also filed as: KEEFER LARRY · KEEFER LARRY K · KEEFER LARRY KAY
55 granted patents·2 pending applications·4,966 citations·filing 1983–2013
99Inventor score
Top patents by PatentIndex Score
57 records- 0199US5155137AComplexes of nitric oxide with polyaminesUS HEALTH·Filed 1990·Granted Oct 13, 1992·176 cites·16 claims
- 0298US6673338B1Nitric oxide-releasing imidate and thioimidate diazeniumdiolates, compositions, uses thereof and method of making sameUS HEALTH·Filed 2001·Granted Jan 6, 2004·100 cites·13 claims
- 0398US6270779B1Nitric oxide-releasing metallic medical devicesUSA·Filed 2000·Granted Aug 7, 2001·170 cites·14 claims
- 0498US5814666AEncapsulated and non-encapsulated nitric oxide generators used as antimicrobial agentsUS HEALTH·Filed 1995·Granted Sep 29, 1998·320 cites·26 claims
- 0598US5405919APolymer-bound nitric oxide/nucleophile adduct compositions, pharmaceutical compositions and methods of treating biological disordersUS HEALTH·Filed 1992·Granted Apr 11, 1995·334 cites·22 claims
- 0697US7928079B2Polysaccharide-derived nitric oxide-releasing carbon-bound diazeniumdiolatesUS HEALTH·Filed 2006·Granted Apr 19, 2011·56 cites·27 claims
- 0797US7105502B2Nitric oxide-releasing imidate and thioimidate diazeniumdiolatesUS HEALTH·Filed 2003·Granted Sep 12, 2006·49 cites·18 claims
- 0897US6511991B2Nitric oxide-releasing amidine- and enamine-derived diazeniumdiolates, compositions and uses thereof and method of making sameUS HEALTH·Filed 2001·Granted Jan 28, 2003·97 cites·26 claims
- 0997US5525357APolymer-bound nitric oxide/nucleophile adduct compositions, pharmaceutical compositions incorporating same and methods of treating biological disorders using sameUS HEALTH·Filed 1993·Granted Jun 11, 1996·258 cites·27 claims
- 1097US5366997AOxygen substituted derivatives of nucleophile-nitric oxide adducts as nitric oxide donor prodrugsUS HEALTH·Filed 1992·Granted Nov 22, 1994·167 cites·25 claims
- 1197US5250550AComplexes of nitric oxide with polyaminesUS HEALTH·Filed 1992·Granted Oct 5, 1993·95 cites·13 claims
- 1296US6911478B2Nitric oxide-releasing amidine- and enamine-derived diazeniumdiolates, compositions and uses thereof and method of making sameUS HEALTH·Filed 2004·Granted Jun 28, 2005·57 cites·29 claims
- 1396US6379660B1Nitric oxide-releasing 1-[(2-carboxylato)pyrrolidin-1-yl] diazen-1-ium-1,2-diolates and composition comprising sameUS HEALTH·Filed 2000·Granted Apr 30, 2002·105 cites·9 claims
- 1496US5910316AUse of nitric oxide-releasing agents to treat impotencyUS HEALTH·Filed 1995·Granted Jun 8, 1999·170 cites·11 claims
- 1596US5683668AMethod of generating nitric oxide gas using nitric oxide complexesUS HEALTH·Filed 1993·Granted Nov 4, 1997·102 cites·12 claims
- 1696US5676963AImplants, prostheses, and stents comprising polymer-bound nitric oxide/nucleophile adducts capable of releasing nitric oxideUS HEALTH·Filed 1995·Granted Oct 14, 1997·144 cites·17 claims
- 1796US5212204AAntihypertensive compositions and use thereofUS HEALTH·Filed 1989·Granted May 18, 1993·138 cites·27 claims
- 1896US4954526AStabilized nitric oxide - primary amine complexes useful as cardiovascular agentsUS HEALTH·Filed 1989·Granted Sep 4, 1990·196 cites·20 claims
- 1995US7348319B2Nitric oxide-releasing amidine diazeniumdiolates, compositions and uses thereof and method of making sameUS HEALTH·Filed 2005·Granted Mar 25, 2008·37 cites·31 claims
- 2095US6703046B2Highly cross-linked, extremely hydrophobic nitric oxide-releasing polymers and methods for their manufacture and useMEDTRONIC AVE INC·Filed 2001·Granted Mar 9, 2004·81 cites·25 claims
- 2195US6232336B1Nitric oxide-releasing amidine- and enamine-derived diazeniumdiolates, compositions and uses thereof and method of making sameUS HEALTH·Filed 1998·Granted May 15, 2001·115 cites·25 claims
- 2295US5691423APolysaccharide-bound nitric oxide-nucleophile adductsUS HEALTH·Filed 1995·Granted Nov 25, 1997·160 cites·4 claims
- 2394US7425218B2Nitric oxide-releasing medical devicesUS HEALTH·Filed 2002·Granted Sep 16, 2008·34 cites·5 claims
- 2494US6750254B2Nitric oxide-releasing amidine—and enamine-derived diazeniumdiolates, compositions and uses thereof and method of making sameUS HEALTH·Filed 2003·Granted Jun 15, 2004·53 cites·16 claims
- 2594US5632981ABiopolymer-bound nitric oxide-releasing compositions, pharmaceutical compositions incorporating same and methods of treating biological disorders using sameUS HEALTH·Filed 1994·Granted May 27, 1997·167 cites·28 claims
- 2693US7226586B2Highly cross-linked, extremely hydrophobic nitric oxide-releasing polymers and methods for their manufacture and useMEDTRONIC VASCULAR INC·Filed 2003·Granted Jun 5, 2007·57 cites·13 claims
- 2793US6949530B2Nitric oxide-releasing amidine diazeniumdiolates, compositions and uses thereof and method of making sameUS HEALTH·Filed 2002·Granted Sep 27, 2005·47 cites·16 claims
- 2893US5650447ANitric oxide-releasing polymers to treat restenosis and related disordersUS HEALTH·Filed 1994·Granted Jul 22, 1997·198 cites·42 claims
- 2992US7081524B2O2-substituted 1-[(2-carboxylato)pyrrolidin-1-yl]diazen-1-ium-1,2-diolatesUS HEALTH·Filed 2005·Granted Jul 25, 2006·15 cites·6 claims
- 3092US5718892APolymer-bound nitric oxide/nucleophile adduct compositions, pharmaceutical compositions incorporating same and methods of treating biological disorders using sameUS HEALTH·Filed 1995·Granted Feb 17, 1998·87 cites·5 claims
- 3192US5039705AAnti-hypertensive compositions of secondary amine-nitric oxide adducts and use thereofUS HEALTH·Filed 1989·Granted Aug 13, 1991·132 cites·14 claims
- 3291US6200558B1Biopolymer-bound nitric oxide-releasing compositions, pharmaceutical compositions incorporating same and methods of treating biological disorders using sameUS HEALTH·Filed 1997·Granted Mar 13, 2001·96 cites·30 claims
- 3391US6110453APolymer-bound nitric oxide/nucleophile adduct compositions, pharmaceutical compositions incorporating same and methods of treating biological disorders using sameUS HEALTH·Filed 1998·Granted Aug 29, 2000·87 cites·18 claims
- 3490US5714511ASelective prevention of organ injury in sepsis and shock using selection release of nitric oxide in vulnerable organsUS HEALTH·Filed 1995·Granted Feb 3, 1998·94 cites·27 claims
- 3589US5814656ASelective prevention of organ injury is sepsis and shock using selective release of nitric oxide vulnerable organsUS HEALTH·Filed 1997·Granted Sep 29, 1998·79 cites·9 claims
- 3688US6911433B2O2-glycosylated 1-substituted diazen-1-ium-1,2-diolatesUS HEALTH·Filed 2003·Granted Jun 28, 2005·34 cites·13 claims
- 3788US6290981B1Use of nitric oxide-releasing agents to treat impotencyUS HEALTH·Filed 1999·Granted Sep 18, 2001·76 cites·10 claims
- 3887US9540471B2Nitric oxide-releasing diazeniumdiolated polyvinylpyrrolidone-based polymers, and compositions, medical devices, and uses thereofUS HEALTH·Filed 2013·Granted Jan 10, 2017·4 cites·20 claims
- 3986US7928096B2Polydiazeniumdiolated cyclic polyamines with polyphasic nitric oxide release and related compounds, compositions comprising same and methods of using sameUS HEALTH·Filed 2008·Granted Apr 19, 2011·14 cites·26 claims
- 4086US6887485B2Nitric oxide-releasing metallic medical devicesUS HEALTH·Filed 2001·Granted May 3, 2005·140 cites·4 claims
- 4185US5208233AAnti-hypertensive compositions of secondary amine-nitric oxide adducts and use thereofUS HEALTH·Filed 1991·Granted May 4, 1993·66 cites·8 claims
- 4283US5721365AN-substituted piperazine NONOatesUS HEALTH·Filed 1995·Granted Feb 24, 1998·69 cites·6 claims
- 4383US5389675AMixed ligand metal complexes of nitric oxide-nucleophile adducts useful as cardiovascular agentsUS HEALTH·Filed 1992·Granted Feb 14, 1995·58 cites·41 claims
- 4482US5700830AUse of nitric oxide-releasing agents for reducing metastasis riskUS ARMY·Filed 1994·Granted Dec 23, 1997·76 cites·4 claims
- 4582US4535154AReductive destruction of nitrosamines, hydrazines, nitramines, azo- and azoxy-compoundsUSA·Filed 1983·Granted Aug 13, 1985·19 cites·24 claims
- 4680US8093343B2Nitric oxide-releasing diazeniumdiolated compoundsHRABIE JOSEPH A·Filed 2011·Granted Jan 10, 2012·3 cites·10 claims
- 4780US6610660B1O2-arylated or O2-glycosylated 1-substituted diazen-1-ium-1,2-diolates and O2-substituted 1-[(2-carboxylato) pyrrolidin-1-yl] diazen-1-ium-1,2-diolatesUS HEALTH·Filed 1997·Granted Aug 26, 2003·45 cites·39 claims
- 4879US7468435B2Polydiazeniumdiolated cyclic polyamines with polyphasic nitric oxide release and related compounds, compositions comprising same and methods of using sameUS HEALTH·Filed 2004·Granted Dec 23, 2008·16 cites·17 claims
- 4976US7968664B2Nitric oxide-releasing diazeniumdiolated acrylonitrile-based polymers, and compositions, medical devices, and uses thereofUS HEALTH·Filed 2005·Granted Jun 28, 2011·3 cites·16 claims
- 5074US5185376ATherapeutic inhibition of platelet aggregation by nucleophile-nitric oxide complexes and derivatives thereofUS HEALTH·Filed 1991·Granted Feb 9, 1993·38 cites·9 claims
Showing the top 50 of 57 patent records by PatentIndex Score.
Identity basis: PatentsView inventor disambiguation (2025Q4-odp release). How scoring works →