Inventor · disambiguated record
Kazuma Tomizuka
Also filed as: TOMIZUKA KAZUMA
29 granted patents·19 pending applications·1,184 citations·filing 1998–2022
97Inventor score
Files withKYOWA HAKKO KIRIN CO LTD16KIRIN BREWERY7KIRIN PHARMA KK6SQUIBB & SONS LLC3TOMIZUKA KAZUMA3
Top patents by PatentIndex Score
48 records- 0199US7041870B2Transgenic transchromosomal rodents for making human antibodiesKIRIN BREWERY·Filed 2001·Granted May 9, 2006·822 cites·4 claims
- 0295US6632976B1Chimeric mice that are produced by microcell mediated chromosome transfer and that retain a human antibody geneKIRIN BREWERY·Filed 1998·Granted Oct 14, 2003·144 cites·54 claims
- 0393US7816578B2Transgenic transchromosomal rodents for making human antibodiesKYOWA HAKKO KIRIN CO LTD·Filed 2005·Granted Oct 19, 2010·11 cites·7 claims
- 0493US7402729B2Human artificial chromosome containing human antibody λ light chain gene and non-human animal containing the human artificial chromosome capable of genetic transmissionKIRIN PHARMA KK·Filed 2005·Granted Jul 22, 2008·13 cites·10 claims
- 0592US7951381B2Method of stimulating epithelial cell proliferation by administration of gastrointestinal proliferative factorKYOWA HAKKO KIRIN CO LTD·Filed 2009·Granted May 31, 2011·18 cites·7 claims
- 0691US7491867B2Expression of xenogenous (human) immunoglobulins in cloned, transgenic ungulatesKYOWA HAKKO KIRIN CO LTD·Filed 2005·Granted Feb 17, 2009·13 cites·36 claims
- 0790US7576258B2Transgenic transchromosomal rodents for making human antibodiesMEDAREX INC·Filed 2005·Granted Aug 18, 2009·7 cites·10 claims
- 0890US7476536B2Artificial human chromosome containing human antibody a light chain geneKIRIN PHARMA KK·Filed 2002·Granted Jan 13, 2009·17 cites·7 claims
- 0989US7414170B2Transgenic bovines capable of human antibody productionKIRIN BREWERY·Filed 2003·Granted Aug 19, 2008·20 cites·39 claims
- 1089US7074983B2Transgenic bovine comprising human immunoglobulin loci and producing human immunoglobulinHEMATECH LLC·Filed 2001·Granted Jul 11, 2006·36 cites·19 claims
- 1188US9426970B2Transgenic transchromosomal rodents for making human antibodiesKYOWA HAKKO KIRIN CO LTD·Filed 2014·Granted Aug 30, 2016·3 cites·17 claims
- 1288US7420099B2Transgenic animals and uses thereofKIRIN HOLDINGS KK·Filed 2005·Granted Sep 2, 2008·7 cites·19 claims
- 1387US9499838B2Human artificial chromosome containing human antibody λ light chain gene and non-human animal containing the human artificial chromosome capable of genetic transmissionKUROIWA YOSHIMI·Filed 2008·Granted Nov 22, 2016·6 cites·24 claims
- 1487US8835712B2Transgenic trasnchromosomal rodents for making human antibodiesTOMIZUKA KAZUMA·Filed 2010·Granted Sep 16, 2014·5 cites·8 claims
- 1586US7928285B2Method of producing xenogenous antibodies using a bovineKYOWA HAKKO KIRIN CO LTD·Filed 2008·Granted Apr 19, 2011·5 cites·6 claims
- 1686US7868223B2Method for modifying chromosomesKYOWA HAKKO KIRIN CO LTD·Filed 2008·Granted Jan 11, 2011·11 cites·7 claims
- 1786US7803981B2Transgenic ungulates capable of human antibody productionKYOWA HAKKO KIRIN CO LTD·Filed 2007·Granted Sep 28, 2010·12 cites·20 claims
- 1884US10448622B2Human artificial chromosome containing human antibody lambda light chain gene and non-human animal containing the human artificial chromosome capable of genetic transmissionSQUIBB & SONS LLC·Filed 2016·Granted Oct 22, 2019·1 cites·10 claims
- 1981US7807863B2Transgenic bovine having reduced prion protein activity and uses thereofKYOWA HAKKO KIRIN CO LTD·Filed 2008·Granted Oct 5, 2010·7 cites·14 claims
- 2078US7429690B2Transgenic bovines having reduced prion protein productionKIRIN HOLDINGS KK·Filed 2003·Granted Sep 30, 2008·14 cites·14 claims
- 2175US2020236915A1Human artificial chromosome containing human antibody lambda light chain gene and non-human animal containing the human artificial chromosome capable of genetic transmissionSQUIBB & SONS LLC·Filed 2019·Application pending·0 cites
- 2274US2021298277A1Human artificial chromosome containing human antibody lambda light chain gene and non-human animal containing the human artificial chromosome capable of genetic transmissionSQUIBB & SONS LLC·Filed 2021·Application pending·0 cites
- 2364US10076103B2Transgenic transchromosomal rodents for making human antibodiesKYOWA HAKKO KIRIN CO LTD·Filed 2016·Granted Sep 18, 2018·0 cites·11 claims
- 2464US2024392313A1Mammalian artificial chromosome vector having human immunoglobulin heavy chain locus comprising modified d-region, and cell or non-human animal retaining the vectorNAT UNIV CORP TOTTORI UNIV·Filed 2022·Application pending·0 cites
- 2564US2011237514A1PHARMACEUTICAL COMPOSITION FOR TREATING BONE DISEASES WHICH COMPRISES PROTEIN COMPRISING Frizzled1, Frizzled2 OR Frizzled7 EXTRACELLULAR CYSTEINE-RICH DOMAINKYOWA HAKKO KIRIN CO LTD·Filed 2009·Application pending·0 cites
- 2664US2024401074A1Method for producing human artificial chromosome vector in human cellNAT UNIV CORP TOTTORI UNIV·Filed 2022·Application pending·0 cites
- 2763US8951789B2Mammalian artificial chromosome vector comprising human cytochrome P450 gene (cluster) and non-human mammalian animal retaining the sameOSHIMURA MITSUO·Filed 2008·Granted Feb 10, 2015·1 cites·1 claims
- 2863US2011067122A1Expression of Xenogenous (Human) Immunoglobulins in cloned, transgenic ungulatesKYOWA HAKKO KIRIN CO LTD·Filed 2009·Application pending·0 cites
- 2962US10646544B2Pharmaceutical composition for treating bone diseases which comprises protein comprising Frizzled 1, Frizzled 2 or Frizzled 7 extracellular cysteine-rich domainKYOWA HAKKO KIRIN CO LTD·Filed 2017·Granted May 12, 2020·0 cites·12 claims
- 3062US8703482B2Human artificial chromosome (HAC) vectorOSHIMURA MITSUO·Filed 2010·Granted Apr 22, 2014·1 cites·5 claims
- 3161US8809045B2Human artificial chromosome (HAC) vector and human cell medicine comprising sameKAKEDA MINORU·Filed 2007·Granted Aug 19, 2014·1 cites·18 claims
- 3260US9700594B2Pharmaceutical composition for treating bone diseases which comprises protein comprising Frizzled1, Frizzled2 or Frizzled7 extracellular cysteine-rich domainKYOWA HAKKO KIRIN CO LTD·Filed 2013·Granted Jul 11, 2017·0 cites·13 claims
- 3360US2010011452A1Chimeric non-human animalKYOWA HAKKO KIRIN CO LTD·Filed 2009·Application pending·0 cites
- 3459US2008300183A1Gastrointestinal proliferative factor and uses thereofKIRIN PHARMA KK·Filed 2007·Application pending·0 cites
- 3558US8110671B2Isolated human chromosome 14 fragment encoding immunoglobulin genesTOMIZUKA KAZUMA·Filed 2007·Granted Feb 7, 2012·0 cites·2 claims
- 3657US8124406B2Method for modifying chromosomesTOMIZUKA KAZUMA·Filed 2010·Granted Feb 28, 2012·0 cites·11 claims
- 3757US2025002963A1A promoter activation sequence, an expression vector comprising the promoter activation sequence, and a mammalian cell comprising the expression vectorTOKYO UNIV OF PHARMACY AND LIFE SCIENCES·Filed 2022·Application pending·0 cites
- 3855US2011231943A1Transgenic animals and uses thereofKYOWA HAKKO KIRIN CO LTD·Filed 2011·Application pending·0 cites
- 3954US2005256044A1Gastrointestinal proliferative factor and uses thereofBOYLE BRYAN J·Filed 2005·Application pending·0 cites
- 4054US2005256036A1Gastrointestinal proliferative factor and uses thereofBOYLE BRYAN J·Filed 2005·Application pending·0 cites
- 4151US2004073957A1Isolation of a rearranged human immunoglobulin gene from a chimeric mouse and recombinant production of the encoded immunoglobulinKIRIN BREWERY·Filed 2003·Application pending·0 cites
- 4251US2009151011A1Chimeric Non-Human Animal and Use ThereofKIRIN PHARMA KK·Filed 2006·Application pending·0 cites
- 4347US7371568B1Method for modifying chromosomesKIRIN PHARMA KK·Filed 1999·Granted May 13, 2008·9 cites·18 claims
- 4446US2005177884A1Chimeric nonhuman animalKIRIN BREWERY·Filed 2002·Application pending·0 cites
- 4545US2006185025A1Human artificial chromosome (hac) vectorKIRIN BREWERY·Filed 2003·Application pending·0 cites
- 4644US2009036369A1Anti-tumor agents comprising r-spondinsKIRIN PHARMA KK·Filed 2006·Application pending·0 cites
- 4744US2006123490A1Pluripotent cells with improved efficiency of homologous recombination and use of the sameKIRIN BREWERY·Filed 2005·Application pending·0 cites
- 4833US2017190781A1Anti-death receptor 3 (dr3) antagonistic antibodies with reduced agonistic activityKYOWA HAKKO KIRIN CO LTD·Filed 2015·Application pending·0 cites
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