Inventor · disambiguated record
Robert L. Coffman
Also filed as: COFFMAN ROBERT · COFFMAN ROBERT L · COFFMAN ROBERT LEE
31 granted patents·9 pending applications·193 citations·filing 1975–2024
96Inventor score
Top patents by PatentIndex Score
40 records- 0195US9993495B2Intrapulmonary administration of polynucleotide toll-like receptor 9 agonists for treating cancer of the lungDYNAVAX TECH CORP·Filed 2016·Granted Jun 12, 2018·9 cites·35 claims
- 0293US10722591B2Cleavable conjugates of TLR7/8 agonist compounds, methods for preparation, and uses thereofDYNAVAX TECH CORP·Filed 2018·Granted Jul 28, 2020·7 cites·121 claims
- 0390US11827641B2Toll-like receptor antagonist compounds and methods of useDYNAVAX TECH CORP·Filed 2022·Granted Nov 28, 2023·1 cites·25 claims
- 0490US10751412B2Combination of a PD-1 antagonist and CPG-C type oligonucleotide for treating cancerMERCK SHARP & DOHME·Filed 2016·Granted Aug 25, 2020·6 cites·28 claims
- 0590US8940310B2Methods of treatment using TLR7 and/or TLR9 inhibitorsBARRAT FRANCK·Filed 2011·Granted Jan 27, 2015·17 cites·33 claims
- 0688US8759305B2Methods and compositions for inhibition of innate immune responses and autoimmunityBARRAT FRANCK·Filed 2005·Granted Jun 24, 2014·12 cites·32 claims
- 0786US11370794B2Toll-like receptor antagonist compounds and methods of useDYNAVAX TECH CORP·Filed 2017·Granted Jun 28, 2022·3 cites·28 claims
- 0884US9950064B2Branched and linear chimeric compounds, polynucleotides, uses and methods for preparation thereofDYNAVAX TECH CORP·Filed 2016·Granted Apr 24, 2018·5 cites·24 claims
- 0983US8962579B2Methods and compositions for inhibition of immune responses and autoimmunityBARRAT FRANCK·Filed 2010·Granted Feb 24, 2015·6 cites·36 claims
- 1083US8815817B2Long term disease modification using immunostimulatory oligonucleotidesHESSEL EDITH M·Filed 2009·Granted Aug 26, 2014·9 cites·22 claims
- 1182US8252757B2Long term disease modification using immunostimulatory oligonucleotidesHESSEL EDITH M·Filed 2007·Granted Aug 28, 2012·9 cites·28 claims
- 1281US11124510B2Alkyl chain modified imidazoquinoline TLR7/8 agonist compounds and uses thereofDYNAVAX TECH CORP·Filed 2020·Granted Sep 21, 2021·1 cites·21 claims
- 1381US5096704AMethod of treating eosinophiliaSCHERING CORP·Filed 1990·Granted Mar 17, 1992·50 cites·4 claims
- 1479US12378255B2Toll-like receptor antagonist compounds and methods of useDYNAVAX TECH CORP·Filed 2023·Granted Aug 5, 2025·0 cites·17 claims
- 1579US2024368155A1Alkyl chain modified imidazoquinoline tlr7/8 agonist compounds and uses thereofDYNAVAX TECH CORP·Filed 2024·Application pending·0 cites
- 1677US12296002B2Immunogenic composition against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)MEDIGEN VACCINE BIOLOGICS CORP·Filed 2021·Granted May 13, 2025·1 cites·14 claims
- 1777US10111899B2Intrapulmonary administration of polynucleotide toll-like receptor 9 agonists for treating cancer of the lungDYNAVAX TECH CORP·Filed 2018·Granted Oct 30, 2018·2 cites·21 claims
- 1873US11981670B2Alkyl chain modified imidazoquinoline TLR7/8 agonist compounds and uses thereofDYNAVAX TECH CORP·Filed 2021·Granted May 14, 2024·0 cites·30 claims
- 1973US4121983AMetal productionALUMINUM CO OF AMERICA·Filed 1977·Granted Oct 24, 1978·16 cites·11 claims
- 2071US10369168B2Administration of polynucleotide toll-like receptor 9 agonists for treating cancerDYNAVAX TECH CORP·Filed 2018·Granted Aug 6, 2019·0 cites·23 claims
- 2171US9347064B2Methods of treatment using TLR7 and/or TLR9 inhibitorsDYNAVAX TECH CORP·Filed 2014·Granted May 24, 2016·1 cites·19 claims
- 2266US9063123B2Transgenic mice expressing human toll-like receptor 8BARRAT FRANCK·Filed 2012·Granted Jun 23, 2015·1 cites·11 claims
- 2363US11918648B2Combination of a PD-1 antagonist and CpG-C type oligonucleotide for treating cancerMERCK SHARP & DOHME LLC·Filed 2020·Granted Mar 5, 2024·0 cites·9 claims
- 2460US10350290B2Linear chimeric compounds and methods of use thereofDYNAVAX TECH CORP·Filed 2018·Granted Jul 16, 2019·0 cites·18 claims
- 2560US2025161430A1IMMUNOGENIC COMPOSITIONS COMPRISING A RECOMBINANT NEURAMINIDASE AND CpG OLIGONUCLEOTIDE ADJUVANT, AND USES THEREOFICAHN SCHOOL MED MOUNT SINAI·Filed 2023·Application pending·0 cites
- 2657US10548975B2Branched chimeric compounds, and methods of use thereofDYNAVAX TECH CORP·Filed 2018·Granted Feb 4, 2020·0 cites·22 claims
- 2756US9333254B2Long term disease modification using immunostimulatory oligonucleotidesDYNAVAX TECH CORP·Filed 2014·Granted May 10, 2016·0 cites·18 claims
- 2853US2015050296A1Methods and compositions for inhibition of innate immune responses and autoimmunityDYNAVAX TECH CORP·Filed 2014·Application pending·0 cites
- 2951US5601815AIL-4 and IL-10 to downregulate delayed-type hypersensitivity and cytokine expresion by T-cellsSCHERING CORP·Filed 1995·Granted Feb 11, 1997·16 cites·17 claims
- 3050US2006193869A1Methods and compositions for induction or promotion of immune toleranceBARRAT FRANCK·Filed 2005·Application pending·0 cites
- 3148US2023072809A1Active booster immunization against tetanus, diphtheria and pertussisDYNAVAX TECH CORP·Filed 2021·Application pending·0 cites
- 3247US9476053B2Methods and compositions for inhibition of immune responses and autoimmunityDYNAVAX TECH CORP·Filed 2015·Granted Oct 25, 2016·0 cites·37 claims
- 3347US6207155B1Method of eosinophil depletion with antibody to CCR 3 receptorSCHERING CORP·Filed 1998·Granted Mar 27, 2001·9 cites·10 claims
- 3447US2016003807A1Tlr8 transgenic animalsDYNAVAX TECH CORP·Filed 2015·Application pending·0 cites
- 3546US2002114806A1Uses of mammalian genes and related reagentsFiled 2001·Application pending·0 cites
- 3644US2011123561A1Methods and compositions for induction or promotion of immune toleranceDYNAVAX TECH CORP·Filed 2010·Application pending·0 cites
- 3743US5676940AMethod of reducing immunoglobulin E responsesSCHERING CORP·Filed 1994·Granted Oct 14, 1997·5 cites·7 claims
- 3838US2018161427A1Combination of an anti-il-10 antibody and a cpg-c type oligonucleotide for treating cancerYU YING·Filed 2016·Application pending·0 cites
- 3935US4259161AProcess for producing aluminum and electrodes for bipolar cellALUMINUM CO OF AMERICA·Filed 1979·Granted Mar 31, 1981·3 cites·12 claims
- 4035US3974080ASilicone hydraulic fluidsUNION CARBIDE CORP·Filed 1975·Granted Aug 10, 1976·4 cites·12 claims
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