Inventor · disambiguated record
Caroline Joy Springer
Also filed as: SPRINGER CAROLINE · SPRINGER CAROLINE J · SPRINGER CAROLINE JOY
42 granted patents·5 pending applications·695 citations·filing 1989–2022
98Inventor score
Files withCANCER RES CAMPAIGN TECH11THE INSTITUTE OF CANCER RES ROYAL CANCER HOSPITAL8CANCER REC TECH LTD7ZENECA LTD5CANCER RESEARCH TECH LTD4
Top patents by PatentIndex Score
47 records- 0197US6916949B2Methods of chemical systhesis of phenolic nitrogen mustard prodrugsCANCER REC TECH LTD·Filed 2002·Granted Jul 12, 2005·62 cites·54 claims
- 0295US5811454A4-amino-fluorobenzamides and their use as cytotoxic prodrugsCANCER RES CAMPAIGN TECH·Filed 1994·Granted Sep 22, 1998·58 cites·13 claims
- 0395US5587161AProdrugs for antibody directed enzyme prodrug therapyZENECA LTD·Filed 1994·Granted Dec 24, 1996·53 cites·21 claims
- 0494US7951819B2Imidazo[4, 5-B]pyridin-2-one and oxazolo[4, 5-B] pyridin-2-one compounds and analogs thereof as cancer therapeutic compoundsCANCER REC TECH LTD·Filed 2007·Granted May 31, 2011·37 cites·46 claims
- 0593US5728868AProdrugs of protein tyrosine kinase inhibitorsCANCER RES CAMPAIGN TECH·Filed 1994·Granted Mar 17, 1998·119 cites·3 claims
- 0690US8198279B2Pyrido[2,3-b]pyrazin-8-substituted compounds and their useSPRINGER CAROLINE JOY·Filed 2008·Granted Jun 12, 2012·18 cites·34 claims
- 0789US7235585B2Enzyme activated self-immolative n-substituted nitrogen mustard prodrugsCANCER REC TECH LTD·Filed 2003·Granted Jun 26, 2007·58 cites·53 claims
- 0888US10995088B2Methylamine derivatives as lysysl oxidase inhibitors for the treatment of cancerTHE INSTITUTE OF CANCER RES ROYAL CANCER HOSPITAL·Filed 2020·Granted May 4, 2021·2 cites·22 claims
- 0988US9120789B21-(5-tert-butyl-2-phenyl-2H-pyrazol-3-yl)-3-[2-fluoro-4-(1-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)-phenyl]-urea and related compounds and their use in therapyCANCER REC TECH LTD·Filed 2014·Granted Sep 1, 2015·7 cites·39 claims
- 1087US9155737B2Pyrido[2,3-B]pyrazin-8-substituted compounds and their useCANCER RES INST ROYAL·Filed 2014·Granted Oct 13, 2015·8 cites·33 claims
- 1187US8912191B2Pyrido[2,3-B]pyrazin-8-substituted compounds and their useCANCER REC TECH LTD·Filed 2013·Granted Dec 16, 2014·8 cites·20 claims
- 1287US8546387B2Pyrido[2,3-b]pyrazin-8-substituted compounds and their useSPRINGER CAROLINE JOY·Filed 2012·Granted Oct 1, 2013·11 cites·32 claims
- 1387US8383816B2Aryl-quinolyl compounds and their useCANCER REC TECH LTD·Filed 2009·Granted Feb 26, 2013·13 cites·29 claims
- 1486US7625922B2Imidazo[4,5-b]pyridin-2-one and oxazolo[4,5-b]pyridin-2-one compounds and analogs thereof as therapeutic compoundsCANCER REC TECH LTD·Filed 2005·Granted Dec 1, 2009·19 cites·44 claims
- 1585US9725447B21-(5-tert-butyl-2-aryl-pyrazol-3-yl)-3-[2-fluoro-4-[(3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]urea derivatives as RAF inhibitors for the treatment of cancerCANCER RES TECH LTD·Filed 2014·Granted Aug 8, 2017·8 cites·45 claims
- 1685US9439893B21-(5-tert-butyl-2-phenyl-2H-pyrazol-3-yl)-3-[2-fluoro-4-(1-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-B]pyridin-7-yloxy)-phenyl]-urea and related compounds and their use in therapyCANCER RES TECH LTD·Filed 2015·Granted Sep 13, 2016·4 cites·29 claims
- 1783US5716990ADrug delivery systemsCANCER RES CAMPAIGN TECH·Filed 1996·Granted Feb 10, 1998·64 cites·6 claims
- 1883US5405990AChemical compoundsZENECA LTD·Filed 1993·Granted Apr 11, 1995·32 cites·13 claims
- 1982US8815896B21-(5-tert-butyl-2-phenyl-2H-pyrazol-3-yl)-3-[2-fluoro-4-(1-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-B]pyridin-7-yloxy)-phenyl]-urea and related compounds and their use in therapySPRINGER CAROLINE·Filed 2011·Granted Aug 26, 2014·7 cites·33 claims
- 2081US9708317B2Process for the preparation of 8-(4-aminophenoxy)-4H-pyrido[2,3-B]pyrazin-3-one derivativesCANCER RES TECH LTD·Filed 2014·Granted Jul 18, 2017·2 cites·83 claims
- 2180US10807974B2Methylamine derivatives as lysysl oxidase inhibitors for the treatment of cancerTHE INSTITUTE OF CANCER RES ROYAL CANCER HOSPITAL·Filed 2017·Granted Oct 20, 2020·2 cites·35 claims
- 2275US9820976B21-(5-tert-butyl-2-phenyl-2H-pyrazol-3-yl)-3-[2-fluoro-4-(1-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)-phenyl]-urea and related compounds and their use in therapyCANCER RESEARCH TECH LTD·Filed 2016·Granted Nov 21, 2017·1 cites·30 claims
- 2375US5977065ABacterial nitroreductase for the reduction of CB1954 and analogues thereof to a cytotoxic formCANCER RES CAMPAIGN TECH·Filed 1998·Granted Nov 2, 1999·16 cites·11 claims
- 2474US5780585ABacterial nitroreductase for the reduction of CB 1954 and analogues thereof to a cytotoxic formCANCER RES CAMPAIGN TECH·Filed 1995·Granted Jul 14, 1998·30 cites·8 claims
- 2573US11325915B2Lysyl oxidase inhibitorsTHE INSTITUTE OF CANCER RES ROYAL CANCER HOSPITAL·Filed 2018·Granted May 10, 2022·1 cites·18 claims
- 2670US6852755B1Nitrogen mustard compounds and prodrugs thereforCANCER RES CAMPAIGN TECH·Filed 2000·Granted Feb 8, 2005·4 cites·52 claims
- 2769US9540372B2Pyrido[2,3-b]pyrazin-8-substituted compounds and their useINST OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (THE)·Filed 2015·Granted Jan 10, 2017·1 cites·37 claims
- 2869US6005002ANitrogen mustard prodrugs with novel lipophilic protecting groups, and processes for their productionCANCER RES CAMPAIGN TECH·Filed 1996·Granted Dec 21, 1999·29 cites·10 claims
- 2968US5714148AChemical compoundsZENECA LTD·Filed 1996·Granted Feb 3, 1998·7 cites·21 claims
- 3067US7737152B26-carboaryl-oxy-pyrazin-2-yl-carboaryl-amines and compositions comprising said compoundsWELLCOME TRUST LTD·Filed 2005·Granted Jun 15, 2010·3 cites·27 claims
- 3165US11608330B2Methylamine derivatives as lysysl oxidase inhibitors for the treatment of cancerTHE INSTITUTE OF CANCER RES ROYAL CANCER HOSPITAL·Filed 2021·Granted Mar 21, 2023·0 cites·34 claims
- 3264US12060360B2Lysyl oxidase inhibitorsTHE INSTITUTE OF CANCER RES ROYAL CANCER HOSPITAL·Filed 2022·Granted Aug 13, 2024·0 cites·16 claims
- 3364US2020216818A1Vaccinia virus for gene-directed enzyme prodrug therapyTHE INSTITUTE OF CANCER RES ROYAL CANCER HOSPITAL·Filed 2019·Application pending·0 cites
- 3457US10100053B2Process for the preparation of 8-(4-aminophenoxy)-4H-pyrido[2,3-b]pyrazin-3-one derivativesCANCER RESEARCH TECH LTD·Filed 2017·Granted Oct 16, 2018·0 cites·2 claims
- 3557US2016130564A1Vaccinia virus for gene-directed enzyme prodrug therapyCANCER RES INST ROYAL·Filed 2014·Application pending·0 cites
- 3656US5958971AChemical compoundsZENECA LTD·Filed 1997·Granted Sep 28, 1999·3 cites·2 claims
- 3750US2024174634A1Aldehyde Dehydrogenase Inhibitors and Their Therapeutic UseCANCER RESEARCH TECH LTD·Filed 2021·Application pending·0 cites
- 3849US6277880B1Chemical compoundsZENECA LTD·Filed 1999·Granted Aug 21, 2001·2 cites·15 claims
- 3948US10167282B21-(5-tert-butyl-2-aryl-pyrazol-3-yl)-3-[2-fluoro-4-[(3-oxo-4H-pyrido [2, 3-B]pyrazin- 8-yl)oxy]phenyl]urea derivatives as RAF inhibitors for the treatment of cancerCANCER RESEARCH TECH LTD·Filed 2017·Granted Jan 1, 2019·0 cites·26 claims
- 4044US6004550AIntracellular expression of carboxypeptidase G2 in a nitrogen mustard prodrug systemCANCER RES CAMPAIGN TECH·Filed 1995·Granted Dec 21, 1999·3 cites·10 claims
- 4143US2022017516A1Lox inhibitorsTHE INSTITUTE OF CANCER RES ROYAL CANCER HOSPITAL·Filed 2019·Application pending·0 cites
- 4241US2004014187A1Bacterial carboxypeptidase cpg2 variants and their use in gene directed enzyme prodrug therapyFiled 2001·Application pending·0 cites
- 4340US12018029B2Hexahydropyrrolo[3,4-c]pyrrole derivatives useful as LOX inhibitorsTHE INSTITUTE OF CANCER RES ROYAL CANCER HOSPITAL·Filed 2019·Granted Jun 25, 2024·0 cites·19 claims
- 4438US6025340ASurface expression of enzyme in gene directed prodrug therapyCANCER RES CAMPAIGN TECH·Filed 1995·Granted Feb 15, 2000·2 cites·23 claims
- 4532US5387707ARoute of synthesis for tertiary alkyl estersFiled 1990·Granted Feb 7, 1995·1 cites·4 claims
- 4631US5359120AImprovements relating to the production of prodrugsCANCER RES CAMPAIGN TECH·Filed 1989·Granted Oct 25, 1994·0 cites·9 claims
- 4729US5770731AImprovements relating to prodrugsCANCER RES CAMPAIGN TECH·Filed 1994·Granted Jun 23, 1998·0 cites·6 claims
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