Inventor · disambiguated record
Ira H. Pastan
Also filed as: PASTAN IRA · PASTAN IRA H
126 granted patents·31 pending applications·4,624 citations·filing 1982–2024
99Inventor score
Top patents by PatentIndex Score
157 records- 0197US7081518B1Anti-mesothelin antibodies having high binding affinityUS HEALTH·Filed 2000·Granted Jul 25, 2006·109 cites·17 claims
- 0297US5602095ARecombinant pseudomonas exotoxin with increased activityUS ARMY·Filed 1995·Granted Feb 11, 1997·200 cites·13 claims
- 0397US4892827ARecombinant pseudomonas exotoxins: construction of an active immunotoxin with low side effectsUS HEALTH·Filed 1986·Granted Jan 9, 1990·180 cites·10 claims
- 0497US4545985APseudomonas exotoxin conjugate immunotoxinsUS HEALTH·Filed 1984·Granted Oct 8, 1985·160 cites·16 claims
- 0596US9868774B2Anti-CD22 chimeric antigen receptorsUS HEALTH·Filed 2012·Granted Jan 16, 2018·36 cites·20 claims
- 0696US9359447B2Anti-mesothelin chimeric antigen receptorsUS HEALTH·Filed 2013·Granted Jun 7, 2016·44 cites·27 claims
- 0796US7355012B2Mutated anti-CD22 antibodies with increased affinity to CD22-expressing leukemia cellsUS HEALTH·Filed 2002·Granted Apr 8, 2008·99 cites·28 claims
- 0896US6558672B1Methods of making recombinant disulfide-stabilized polypeptide fragments having binding specificityUS HEALTH·Filed 2000·Granted May 6, 2003·68 cites·2 claims
- 0995US5854044ARecombinant pseudomonas exotoxin with increased activityNAT INST HEALTH·Filed 1995·Granted Dec 29, 1998·135 cites·13 claims
- 1095US5747654ARecombinant disulfide-stabilized polypeptide fragments having binding specificityUS HEALTH·Filed 1993·Granted May 5, 1998·140 cites·27 claims
- 1195US5512658APseudomonas exotoxins (PE) and conjugates thereof having lower animal toxicity with high cytocidal activity through substitution of positively charged amino acidsUS HEALTH·Filed 1993·Granted Apr 30, 1996·149 cites·9 claims
- 1295US5489525AMonoclonal antibodies to prostate cellsUS ARMY·Filed 1992·Granted Feb 6, 1996·171 cites·11 claims
- 1394US9803022B2Mesothelin domain-specific monoclonal antibodies and use thereofUS HEALTH·Filed 2016·Granted Oct 31, 2017·15 cites·28 claims
- 1494US9416190B2Mesothelin antibodies and methods for eliciting potent antitumor activityUS HEALTH·Filed 2013·Granted Aug 16, 2016·31 cites·28 claims
- 1594US9175057B2Immunogenic peptides and methods of useSCHLOM JEFFREY·Filed 2011·Granted Nov 3, 2015·18 cites·36 claims
- 1694US7521054B2Reduction of the nonspecific animal toxicity of immunotoxins by mutating the framework regions of the Fv to lower the isoelectric pointUS HEALTH·Filed 2001·Granted Apr 21, 2009·72 cites·8 claims
- 1794US5608039ASingle chain B3 antibody fusion proteins and their usesUS HEALTH·Filed 1994·Granted Mar 4, 1997·163 cites·18 claims
- 1893US8460660B2Anti-mesothelin antibodiesHO MITCHELL·Filed 2010·Granted Jun 11, 2013·19 cites·19 claims
- 1993US8357783B2Human anti-mesothelin monoclonal antibodiesUS HEALTH·Filed 2009·Granted Jan 22, 2013·22 cites·23 claims
- 2093US7777019B2Mutated Anti-CD22 antibodies with increased affinity to CD22-expressing leukemia cellsUS HEALTH·Filed 2008·Granted Aug 17, 2010·16 cites·24 claims
- 2193US6011002ACircularly permuted ligands and circularly permuted chimeric moleculesUS HEALTH·Filed 1995·Granted Jan 4, 2000·116 cites·50 claims
- 2293US5614191AIL-13 receptor specific chimeric proteins and uses thereofUS HEALTH·Filed 1995·Granted Mar 25, 1997·118 cites·21 claims
- 2392US10703816B2M971 chimeric antigen receptorsUS HEALTH·Filed 2018·Granted Jul 7, 2020·3 cites·18 claims
- 2492US9409992B2Mesothelin domain-specific monoclonal antibodies and use thereofUS HEALTH·Filed 2013·Granted Aug 9, 2016·16 cites·27 claims
- 2592US7709252B2Antibodies, including FV molecules, and immunoconjugates having high binding affinity for mesothelin and methods for their useUS HEALTH·Filed 2008·Granted May 4, 2010·13 cites·16 claims
- 2692US7368110B2Antibodies, including Fv molecules, and immunoconjugates having high binding affinity for mesothelin and methods for their useUS HEALTH·Filed 2004·Granted May 6, 2008·38 cites·11 claims
- 2792US6423513B1Polynucleotides encoding protease-activatable pseudomonas exotoxin a-like proproteinsUS HEALTH·Filed 2000·Granted Jul 23, 2002·30 cites·5 claims
- 2892US5696237ARecombinant antibody-toxin fusion proteinUS HEALTH·Filed 1995·Granted Dec 9, 1997·91 cites·5 claims
- 2991US9598492B2Human monoclonal antibodies specific for CD22THE US SECRETARY OF THE DEPT OF HEALTH AND HUMAN SERVICES·Filed 2016·Granted Mar 21, 2017·8 cites·13 claims
- 3091US9388222B2Modified Pseudomonas exotoxin AUS HEALTH·Filed 2014·Granted Jul 12, 2016·15 cites·42 claims
- 3191US7982011B2Mutated anti-cd22 antibodies and immunoconjugatesUS HEALTH·Filed 2004·Granted Jul 19, 2011·57 cites·40 claims
- 3291US5821238ARecombinant pseudomonas exotoxin with increased activityUS ARMY·Filed 1995·Granted Oct 13, 1998·104 cites·6 claims
- 3390US9279019B2Human monoclonal antibodies specific for CD22US HEALTH·Filed 2013·Granted Mar 8, 2016·10 cites·23 claims
- 3490US8871906B2Deletions in domain II of pseudomonas exotoxin a that remove immunogenic epitopesPASTAN IRA H·Filed 2008·Granted Oct 28, 2014·27 cites·41 claims
- 3590US8809502B2Mutated anti-CD22 antibodies with increased affinity to CD22-expressing leukemia cellsPASTAN IRA·Filed 2012·Granted Aug 19, 2014·12 cites·18 claims
- 3690US8591889B2Human monoclonal antibodies specific for CD22DIMITROV DIMITER S·Filed 2009·Granted Nov 26, 2013·12 cites·23 claims
- 3790US7541034B1Recombinant antibodies and immunoconjugates targeted to CD-22 bearing cells and tumorsUS HEALTH·Filed 1998·Granted Jun 2, 2009·93 cites·1 claims
- 3890US7375183B1Mesothelin, immunogenic peptides derived therefrom, and compositions comprising mesothelin, or immunogenic peptides thereofUS HEALTH·Filed 2000·Granted May 20, 2008·23 cites·3 claims
- 3990US6083502AMesothelium antigen and methods and kits for targeting itUS HEALTH·Filed 1997·Granted Jul 4, 2000·98 cites·31 claims
- 4089US7999077B2IRTA2 antibodies and methods of useUS HEALTH·Filed 2005·Granted Aug 16, 2011·23 cites·17 claims
- 4189US6809184B1Antibodies, including FV molecules, and immunoconjugates having high binding affinity for mesothelin and methods for their useUS HEALTH·Filed 1998·Granted Oct 26, 2004·69 cites·52 claims
- 4289US5889157AHumanized B3 antibody fragments, fusion proteins, and uses thereofUS HEALTH·Filed 1994·Granted Mar 30, 1999·64 cites·21 claims
- 4388US10925969B2Anti-BCMA polypeptides and proteinsUS HEALTH·Filed 2016·Granted Feb 23, 2021·6 cites·25 claims
- 4488US10072078B2M971 chimeric antigen receptorsUS HEALTH·Filed 2013·Granted Sep 11, 2018·7 cites·18 claims
- 4588US9206240B2Pseudomonas exotoxin A with less immunogenic B cell epitopesPASTAN IRA H·Filed 2012·Granted Dec 8, 2015·8 cites·14 claims
- 4688US8039593B2Antibodies and immunotoxins that target human glycoprotein NMBUNIV DUKE·Filed 2006·Granted Oct 18, 2011·10 cites·32 claims
- 4788US7910692B2Immunogenic peptides and methods of useUS HEALTH·Filed 2007·Granted Mar 22, 2011·7 cites·39 claims
- 4888US6153430ANucleic acid encoding mesothelin, a differentiation antigen present on mesothelium, mesotheliomas and ovarian cancersUS HEALTH·Filed 1998·Granted Nov 28, 2000·81 cites·4 claims
- 4988US5919456AIL-13 receptor specific chimeric proteinsUS HEALTH·Filed 1997·Granted Jul 6, 1999·70 cites·14 claims
- 5088US5635599AFusion proteins comprising circularly permuted ligandsUS HEALTH·Filed 1994·Granted Jun 3, 1997·72 cites·17 claims
Showing the top 50 of 157 patent records by PatentIndex Score.
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