Inventor · disambiguated record
Barbara Kure Klein
Also filed as: KLEIN BARBARA · KLEIN BARBARA J · KLEIN BARBARA K · KLEIN BARBARA KURE
38 granted patents·14 pending applications·802 citations·filing 1993–2025
98Inventor score
Top patents by PatentIndex Score
52 records- 0191US5858347ATherapeutic methods using fusion proteins between interleukin-3 (IL-3) variants and other hematopoietic factorsSEARLE & CO·Filed 1995·Granted Jan 12, 1999·83 cites·53 claims
- 0288US6440407B1Methods of ex-vivo expansion of hematopoietic cells using interleukin-3 (IL-3) multiple mutation polypeptidesSEARLE & CO·Filed 1996·Granted Aug 27, 2002·37 cites·24 claims
- 0388US5997860AEx-vivo expansion of stem cells using combinations of interleukin-3 (IL-3) variants and other cytokinesSEARLE & CO·Filed 1995·Granted Dec 7, 1999·68 cites·44 claims
- 0486US7348021B2Immunostimulating coating for surgical devicesBRENNEN MEDICAL LLC·Filed 2003·Granted Mar 25, 2008·53 cites·4 claims
- 0585US6730303B1Fused G-CSF and IL-3 proteins and uses thereofPHARMACIA CORP·Filed 2000·Granted May 4, 2004·12 cites·27 claims
- 0684US6541678B2Immunostimulating coating for surgical devicesBRENNEN MEDICAL INC·Filed 2001·Granted Apr 1, 2003·46 cites·16 claims
- 0783US6030812AFusion proteins comprising multiply mutated interleukin-3 (IL-3) polypeptides and second growth factorsSEARLE & CO·Filed 1995·Granted Feb 29, 2000·47 cites·66 claims
- 0881US5980918Aβ-D-glucan topical compositionBRENNEN MEDICAL INC·Filed 1997·Granted Nov 9, 1999·45 cites·21 claims
- 0981US5772992ACompositions for co-administration of interleukin-3 mutants and other cytokines and hematopoietic factorsSEARLE & CO·Filed 1994·Granted Jun 30, 1998·36 cites·23 claims
- 1080US5677149AInterleukin-3 (IL-3) mutant polypeptides and their recombinant productionSEARLE & CO·Filed 1993·Granted Oct 14, 1997·27 cites·97 claims
- 1178US8231894B2Antimicrobial and immunostimulating compositionKLEIN BARBARA K·Filed 2011·Granted Jul 31, 2012·5 cites·21 claims
- 1278US6361977B1Methods of using multivariant IL-3 hematopoiesis fusion proteinFiled 1995·Granted Mar 26, 2002·33 cites·62 claims
- 1374US6074639AEx vivo expansion of hematopoietic cells using interleukin-3 (IL-3) variant fusion proteinsSEARLE & CO·Filed 1995·Granted Jun 13, 2000·20 cites·60 claims
- 1474US6022535ATreatment of hematopoietic disorders with fusion proteins comprising multiply mutated interleukin-3 (IL-3) polypeptides and second growth factorsSEARLE & CO·Filed 1995·Granted Feb 8, 2000·21 cites·62 claims
- 1574US5604116AInterleukin-3 (IL-3) multiple mutation polypeptides, recombinant production of the same, and corresponding therapeutic methodsSEARLE & CO·Filed 1993·Granted Feb 18, 1997·20 cites·31 claims
- 1673US6066318AMulti-functional hematopoietic fusion proteins between sequence rearranged C-MPL receptor agonists and other hematopoietic factorsSEARLE & CO·Filed 1997·Granted May 23, 2000·22 cites·58 claims
- 1772US6057133AMultivariant human IL-3 fusion proteins and their recombinant productionSEARLE & CO·Filed 1994·Granted May 2, 2000·22 cites·70 claims
- 1872US5738849AInterleukin-3 (IL-3) variant fusion proteins, their recombinant production, and therapeutic compositions comprising themSEARLE & CO·Filed 1994·Granted Apr 14, 1998·23 cites·44 claims
- 1971US6436387B1Methods of ex-vivo expansion of hematopoietic cells using multivariant IL-3 hematopoiesis chimera proteinsSEARLE & CO·Filed 1996·Granted Aug 20, 2002·19 cites·48 claims
- 2070US6132991AHuman interleukin-3 (IL-3) variant fusion proteinsSEARLE & CO·Filed 1995·Granted Oct 17, 2000·15 cites·60 claims
- 2170US6100070AG-CSF receptor agonistsSEARLE & CO·Filed 1997·Granted Aug 8, 2000·35 cites·21 claims
- 2269US2005244372A1Interleukin-3 (IL-3) multiple mutation polypeptidesBAUER S C·Filed 2004·Application pending·0 cites
- 2365US6168799B1β-D-glucan topical compositionBRENNEN MEDICAL INC·Filed 1999·Granted Jan 2, 2001·21 cites·8 claims
- 2465US6051217ATherapeutic uses of interleukin-3 (IL-3) multiple mutation polypeptidesSEARLE & CO·Filed 1995·Granted Apr 18, 2000·15 cites·132 claims
- 2563US2006240083A1Antimicrobial and immunostimulating compositionBRENNEN MEDICAL LLC·Filed 2006·Application pending·0 cites
- 2663US2003103936A1Method of ex-vivo expansion of hematopoeitic cells using interleukin-3 (IL-3) multiple mutation polypeptidesFiled 2002·Application pending·0 cites
- 2761US6060047ACo-administration of interleukin-3 mutant polypeptides with CSF's for multi-lineage hematopoietic cell productionSEARLE & CO·Filed 1995·Granted May 9, 2000·16 cites·31 claims
- 2861US2004171115A1Multi-functional hematopoietic fusion proteins between sequence rearranged G-CSF receptor agonists and other hematopoietic factorsFiled 2003·Application pending·0 cites
- 2961US2003220472A1Interleukin-3 (IL-3) multiple mutation polypeptidesFiled 2002·Application pending·0 cites
- 3058US6153183ACo-administration of interleukin-3 mutant polypeptides with CSF's or cytokines for multi-lineage hematopoietic cell productionSEARLE & CO·Filed 1994·Granted Nov 28, 2000·15 cites·33 claims
- 3158US6093395ACo-administration of interleukin-3 mutant polypeptides with CSF's for multi-lineage hematopoietic cell productionSEARLE & CO·Filed 1995·Granted Jul 25, 2000·14 cites·56 claims
- 3255US2003165461A1Methods of ex-vivo expansion of hematopoeitic cells using interleukin-3 mutant polypeptides with other hematopoietic growth factorsFiled 2002·Application pending·0 cites
- 3355US2005059149A1Methods of ex-vivo expansion of hematopoeitic cells using multivariant IL-3 hematopoiesis chimera proteinsFiled 2004·Application pending·0 cites
- 3454US2003185790A1Methods of ex-vivo expansion of hematopoeitic cells using multivariant IL-3 hematopoiesis chimera proteinsFiled 2002·Application pending·0 cites
- 3553US2003194783A1Co-administration of interleukin-3 mutant polypeptides with CSF's for multi-lineage hematopoietic cell productionFiled 2002·Application pending·0 cites
- 3653US2004005364A1Antimicrobial and immunostimulating compositionFiled 2003·Application pending·0 cites
- 3751US5501962AInterleuken-3 (IL-3) human/murine hybrid polypeptides and recombinant production of the sameSEARLE & CO·Filed 1993·Granted Mar 26, 1996·9 cites·17 claims
- 3850US2002156650A1Secure distribution of digital healthcare data using an offsite internet file serverFiled 2001·Application pending·0 cites
- 3948US2025295699A1Methods and compositions for treating cortical hyperexcitability and reversing stroke-induced changes in gene expression and protein expressionSANBIO INC·Filed 2025·Application pending·0 cites
- 4046US2005037439A1Differentially expressed genes involved in cancer, the polypeptides encoded thereby, and methods of using the sameFiled 2003·Application pending·0 cites
- 4144US6413509B1Methods of ex-vivo expansion of hematopoietic cells using interleukin-3 mutant polypeptides with other hematopoietic growth factorsFiled 1996·Granted Jul 2, 2002·3 cites·35 claims
- 4242US5543141ATherapeutic methods using interleukin-3 (IL-3) human/murine hybrid polypeptidesSEARLE & CO·Filed 1995·Granted Aug 6, 1996·5 cites·1 claims
- 4340US6361976B1Co-administration of interleukin-3 mutant polypeptides with CSF'S for multi-lineage hematopoietic cell productionFiled 1995·Granted Mar 26, 2002·2 cites·38 claims
- 4439US6479261B1Methods of using interleukin-3 (IL-3) mutant polypeptides for ex-vivo expansion of hematopoietic stem cellsPHARMACIA CORP·Filed 1995·Granted Nov 12, 2002·2 cites·22 claims
- 4536US6379662B1Co-administration of interleukin-3 mutant polypeptides with CSF's for multi-lineage hematopoietic cell productionFiled 1995·Granted Apr 30, 2002·2 cites·10 claims
- 4634US6458931B1Interleukin-3 (IL-3) multiple mutation polypeptidesFiled 1995·Granted Oct 1, 2002·1 cites·36 claims
- 4734US2004018618A1Interleukin-3 (IL-3) mutant polypeptidesFiled 2002·Application pending·0 cites
- 4833US7091319B1IL-3 variant hematopoiesis fusion proteinBAUER S CHRISTOPHER·Filed 1995·Granted Aug 15, 2006·2 cites·36 claims
- 4933US6133506AKeto-acyl-(ACP) reductase promoter from cuphea lanceolataMAX PLANCK GES ZUR FORERUNG DE·Filed 1994·Granted Oct 17, 2000·4 cites·10 claims
- 5032US5997857ACo-administration of interleukin-3 mutants with colony stimulating factorsSEARLE & CO·Filed 1995·Granted Dec 7, 1999·0 cites·50 claims
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