Inventor · disambiguated record
Mark Edward Ruppen
Also filed as: RUPPEN MARK · RUPPEN MARK E · RUPPEN MARK EDWARD
61 granted patents·25 pending applications·657 citations·filing 1990–2025
99Inventor score
Top patents by PatentIndex Score
86 records- 0197US10550159B2Neisseria meningitidis composition and methods thereofPFIZER·Filed 2018·Granted Feb 4, 2020·11 cites·15 claims
- 0297US10196429B2Neisseria meningitidis composition and methods thereofPFIZER·Filed 2017·Granted Feb 5, 2019·12 cites·5 claims
- 0397US9187536B1Compositions relating to a mutant Clostridium difficile toxin and methods thereofWYETH LLC·Filed 2015·Granted Nov 17, 2015·19 cites·20 claims
- 0496US10982198B2Compositions and methods relating to a mutant Clostridium difficile toxinPFIZER·Filed 2018·Granted Apr 20, 2021·4 cites·17 claims
- 0596US10774117B2Compositions relating to a mutant clostridium difficile toxin and methods thereofWYETH LLC·Filed 2017·Granted Sep 15, 2020·6 cites·31 claims
- 0696US9724402B2Neisseria meningitidis composition and methods thereofPFIZER·Filed 2016·Granted Aug 8, 2017·22 cites·10 claims
- 0796US9561269B2Neisseria meningitidis compositions and methods thereofPFIZER·Filed 2015·Granted Feb 7, 2017·19 cites·12 claims
- 0896US7445916B2Process for preparing rapamycin 42-esters and FK-506 32-esters with dicarboxylic acid, precursors for rapamycin conjugates and antibodiesWYETH CORP·Filed 2005·Granted Nov 4, 2008·22 cites·12 claims
- 0995US11208633B2Compositions and methods relating to a mutant Clostridium difficile toxinPFIZER·Filed 2019·Granted Dec 28, 2021·3 cites·15 claims
- 1095US11077180B2Non-lipidated variants of Neisseria meningitidis ORF2086 antigensWYETH LLC·Filed 2019·Granted Aug 3, 2021·8 cites·2 claims
- 1195US10226525B2Group B Streptococcus polysaccharide-protein conjugates, methods for producing conjugates, immunogenic compositions comprising conjugates, and uses thereofPFIZER·Filed 2016·Granted Mar 12, 2019·18 cites·32 claims
- 1295US9745354B2Compositions relating to a mutant Clostridium difficile toxin and methods thereofWYETH LLC·Filed 2014·Granted Aug 29, 2017·15 cites·28 claims
- 1395USRE46518ECompositions relating to a mutant Clostridium difficile toxin and methods thereofWYETH LLC·Filed 2016·Granted Aug 22, 2017·9 cites·48 claims
- 1495US8986710B2Neisseria meningitidis compositions and methods thereofPFIZER·Filed 2013·Granted Mar 24, 2015·26 cites·8 claims
- 1595US8900597B2Compositions relating to a mutant Clostridium difficile toxin and methods thereofWYETH LLC·Filed 2013·Granted Dec 2, 2014·15 cites·41 claims
- 1695US8481692B2Compositions relating to a mutant Clostridium difficile toxin and methods thereofSIDHU MANINDER K·Filed 2012·Granted Jul 9, 2013·30 cites·20 claims
- 1795US8153768B2Calicheamicin derivative-carrier conjugatesKUNZ ARTHUR·Filed 2003·Granted Apr 10, 2012·114 cites·5 claims
- 1894USRE48862ECompositions relating to a mutant Clostridium difficile toxin and methods thereofWYETH LLC·Filed 2019·Granted Dec 28, 2021·3 cites·20 claims
- 1994US10597428B2Compositions relating to a mutant clostridium difficile toxin and methods thereofWYETH LLC·Filed 2019·Granted Mar 24, 2020·7 cites·20 claims
- 2094US9802987B2Immunogenic fusion polypeptidesPFIZER·Filed 2014·Granted Oct 31, 2017·17 cites·6 claims
- 2193USRE48863ECompositions relating to a mutant Clostridium difficile toxin and methods thereofWYETH LLC·Filed 2019·Granted Dec 28, 2021·3 cites·20 claims
- 2293US10829521B2Neisseria meningitidis composition and methods thereofPFIZER·Filed 2019·Granted Nov 10, 2020·5 cites·1 claims
- 2393US10512681B2Non-lipidated variants of Neisseria meningitidis ORF2086 antigensWYETH LLC·Filed 2017·Granted Dec 24, 2019·12 cites·20 claims
- 2493US7538119B241-Methoxy isotope labeled rapamycin 42-esterWYETH CORP·Filed 2006·Granted May 26, 2009·12 cites·25 claims
- 2592US10946086B2Group B Streptococcus polysaccharide-protein conjugates, methods for producing conjugates, immunogenic compositions comprising conjugates, and uses thereofPFIZER·Filed 2019·Granted Mar 16, 2021·5 cites·7 claims
- 2692US10787652B2Compositions and methods relating to a mutant clostridium difficile toxinPFIZER·Filed 2013·Granted Sep 29, 2020·6 cites·17 claims
- 2792US7268144B2Regiospecific synthesis of rapamycin 42-ester derivativesWYETH CORP·Filed 2005·Granted Sep 11, 2007·23 cites·14 claims
- 2891US11535652B2Compositions relating to a mutant clostridium difficile toxin and methods thereofWYETH LLC·Filed 2019·Granted Dec 27, 2022·2 cites·19 claims
- 2990US7202256B2Proline CCI-779, production of and uses therefor, and two-step enzymatic synthesis of proline CCI-779 and CCI-779WYETH CORP·Filed 2005·Granted Apr 10, 2007·15 cites·14 claims
- 3089US9950058B2RSV F protein mutantsPFIZER·Filed 2016·Granted Apr 24, 2018·9 cites·44 claims
- 3189US9757443B2Non-lipidated variants of Neisseria meningitidis ORF2086 antigensANDERSON ANNALIESA SYBIL·Filed 2011·Granted Sep 12, 2017·16 cites·11 claims
- 3288US8835611B2Calicheamicin derivative-carrier conjugatesKUNZ ARTHUR·Filed 2012·Granted Sep 16, 2014·10 cites·40 claims
- 3388US8652480B2Shortened purification process for the production of capsular Streptococcus pneumoniae polysaccharidesYUAN YONGHUI·Filed 2008·Granted Feb 18, 2014·21 cites·3 claims
- 3488US2025002875A1Compositions and methods relating to a mutant clostridium difficile toxinPFIZER·Filed 2024·Application pending·0 cites
- 3587US9675681B2Shortened purification process for the production of capsular Streptococcus pneumoniae polysaccharidesWYETH LLC·Filed 2015·Granted Jun 13, 2017·7 cites·12 claims
- 3687US2023391835A1Compositions relating to a mutant clostridium difficile toxin and methods thereofWYETH LLC·Filed 2022·Application pending·0 cites
- 3786US7396660B2Cloning genes from Streptomyces cyaneogriseus subsp. Noncyanogenus for biosynthesis of antibiotics and methods of useWYETH CORP·Filed 2004·Granted Jul 8, 2008·19 cites·8 claims
- 3885US11260119B2Escherichia coli compositions and methods thereofPFIZER·Filed 2019·Granted Mar 1, 2022·3 cites·25 claims
- 3985US7605257B2Processes for preparing water-soluble polyethylene glycol conjugates of macrolide immunosuppressantsWYETH CORP·Filed 2007·Granted Oct 20, 2009·7 cites·23 claims
- 4084US12364749B2RSV F protein mutantsPFIZER·Filed 2023·Granted Jul 22, 2025·0 cites·18 claims
- 4184US8889145B2Immunogenic compositions of Staphylococcus aureus antigensWYETH LLC·Filed 2013·Granted Nov 18, 2014·6 cites·18 claims
- 4284US8568735B2Immunogenic compositions of Staphylococcus aureus antigensANDERSON ANNALIESA·Filed 2010·Granted Oct 29, 2013·12 cites·22 claims
- 4384US7718791B2Separation of contaminants from Streptococcus pneumoniae polysaccharide by pH manipulationWYETH LLC·Filed 2006·Granted May 18, 2010·10 cites·14 claims
- 4484US2025312435A1RSV F Protein MutantsPFIZER·Filed 2025·Application pending·0 cites
- 4583US9114105B2Immunogenic compositions of Staphylococcus aureus antigensWYETH LLC·Filed 2014·Granted Aug 25, 2015·5 cites·14 claims
- 4683US8999697B2Shortened purification process for the production of capsular Streptococcus pneumoniae polysaccharidesWYETH LLC·Filed 2014·Granted Apr 7, 2015·7 cites·41 claims
- 4783US7332601B2CCI-779 derivatives and methods of making sameWYETH CORP·Filed 2005·Granted Feb 19, 2008·9 cites·10 claims
- 4882US10821171B2RSV F protein mutantsPFIZER·Filed 2019·Granted Nov 3, 2020·1 cites·20 claims
- 4982US9351986B2Calicheamicin derivative-carrier conjugatesWYETH HOLDINGS LLC·Filed 2014·Granted May 31, 2016·4 cites·22 claims
- 5080US8747857B2Calicheamicin derivative-carrier conjugatesKUNZ ARTHUR·Filed 2003·Granted Jun 10, 2014·10 cites·96 claims
Showing the top 50 of 86 patent records by PatentIndex Score.
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