Inventor · disambiguated record
Jan M.A. Van Deursen
Also filed as: VAN DEURSEN JAN · VAN DEURSEN JAN M A
17 granted patents·9 pending applications·115 citations·filing 2003–2025
94Inventor score
Files withBUCK INST RES AGING10MAYO FOUND MEDICAL EDUCATION & RES7UNITY BIOTECHNOLOGY INC4CAVALRY BIOSCIENCES INC2MAYO FOUNDATION2
Top patents by PatentIndex Score
26 records- 0198US10010546B2Treatment of ophthalmic conditions by selectively removing senescent cells from the eyeBUCK INST RES AGING·Filed 2017·Granted Jul 3, 2018·23 cites·11 claims
- 0297US9968076B2Transgenic animals capable of being induced to delete senescent cellsMAYO FOUND MEDICAL EDUCATION & RES·Filed 2015·Granted May 15, 2018·19 cites·31 claims
- 0396US9993472B2Treatment for osteoarthritis in a joint by administering a means for inhibiting MDM2BUCK INST RES AGING·Filed 2015·Granted Jun 12, 2018·20 cites·7 claims
- 0496US9980962B2Use of sulfonamide inhibitors of Bcl-2 to treat senescence-associated lung conditions such as pulmonary fibrosis and chronic obstructive pulmonary diseaseBUCK INST RES AGING·Filed 2017·Granted May 29, 2018·6 cites·8 claims
- 0595US10328073B2Use of sulfonamide inhibitors of BCL-2 and BCL-xL to treat ophthalmic disease by selectively removing senescent cellsUNITY BIOTECHNOLOGY INC·Filed 2018·Granted Jun 25, 2019·9 cites·16 claims
- 0694US10478432B2Compositions of matter for treatment of ophthalmic conditions by selectively removing senescent cells from the eyeBUCK INST RES AGING·Filed 2018·Granted Nov 19, 2019·7 cites·18 claims
- 0792US10517866B2Removing senescent cells from a mixed cell population or tissue using a phosphoinositide 3-kinase (PI3K) inhibitorUNITY BIOTECHNOLOGY INC·Filed 2018·Granted Dec 31, 2019·5 cites·15 claims
- 0892US10258618B2Treating pulmonary conditions by selectively removing senescent cells from the lung using an intermittent dosing regimenBUCK INST RES AGING·Filed 2018·Granted Apr 16, 2019·5 cites·17 claims
- 0991US10328058B2Treating atherosclerosis by removing senescent foam cell macrophages from atherosclerotic plaquesMAYO FOUND MEDICAL EDUCATION & RES·Filed 2017·Granted Jun 25, 2019·5 cites·12 claims
- 1090US11351167B2Treating cognitive decline and other neurodegenerative conditions by selectively removing senescent cells from neurological tissueBUCK INST RES AGING·Filed 2019·Granted Jun 7, 2022·1 cites·14 claims
- 1190US10478433B2Unit dose of an aryl sulfonamide that is effective for treating eye disease and averting potential vision lossUNITY BIOTECHNOLOGY INC·Filed 2018·Granted Nov 19, 2019·4 cites·20 claims
- 1290US10413542B2Methods and compositions for killing senescent cells and for treating senescence-associated diseases and disorders using an inhibitor of Akt kinaseBUCK INST RES AGING·Filed 2018·Granted Sep 17, 2019·4 cites·12 claims
- 1382US12285427B2Treatment of a senescence-associated ocular disease or disorder using a Bcl-xL selective inhibitorBUCK INST RES AGING·Filed 2023·Granted Apr 29, 2025·0 cites·4 claims
- 1478US11963957B2Treating cardiovascular disease by selectively eliminating senescent cellsBUCK INST RES AGING·Filed 2020·Granted Apr 23, 2024·0 cites·24 claims
- 1577US2021030752A1Treating cognitive decline and other neurodegenerative conditions by selectively removing senescent cells from neurological tissueBUCK INST RES AGING·Filed 2020·Application pending·0 cites
- 1672US2025368711A1Compositions and methods for treating meibomian gland dysfunctionCAVALRY BIOSCIENCES INC·Filed 2025·Application pending·0 cites
- 1769US2025376500A1Compositions and methods for treating meibomian gland dysfunctionCAVALRY BIOSCIENCES INC·Filed 2025·Application pending·0 cites
- 1866US10251376B2Increasing healthy lifespan and delaying progression of age-related phenotypes by selectively removing senescent cellsMAYO FOUND MEDICAL EDUCATION & RES·Filed 2018·Granted Apr 9, 2019·0 cites·12 claims
- 1965US2018279590A1Nucleic Acid Construct Comprising a P16 Promoter Controlling Expression of a Transgene that Causes Apoptosis in Senescent CellsMAYO FOUND MEDICAL EDUCATION & RES·Filed 2018·Application pending·0 cites
- 2062US2019022225A1Protocol for increasing life expectancy in a test subjectMAYO FOUND MEDICAL EDUCATION & RES·Filed 2018·Application pending·0 cites
- 2162US2024382563A1Promoting immune surveillance against cancer cellsMAYO FOUND MEDICAL EDUCATION & RES·Filed 2022·Application pending·0 cites
- 2260US7220892B2Transgenic mouse lacking PAPP-A activityMAYO FOUNDATION·Filed 2003·Granted May 22, 2007·4 cites·6 claims
- 2359US7098377B2IEX-1 knockout animalsMAYO FOUNDATION·Filed 2004·Granted Aug 29, 2006·3 cites·6 claims
- 2458US2014189897A1Transgenic animals capable of being induced to delete senescent cellsKIRKLAND JAMES L·Filed 2012·Application pending·0 cites
- 2551US2018193458A1Compositions and methods for treating senescence-associated diseases and disordersUNITY BIOTECHNOLOGY INC·Filed 2016·Application pending·0 cites
- 2649US2019000846A1Pharmaceutical Products and Drug Combinations for Treating Atherosclerosis by Stabilizing Atherosclerotic Plaques and Promoting Plaque RegressionMAYO FOUND MEDICAL EDUCATION & RES·Filed 2018·Application pending·0 cites
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