Inventor · disambiguated record
Tamar Tchkonia
Also filed as: TCHKONIA TAMAR
21 granted patents·14 pending applications·157 citations·filing 2012–2024
96Inventor score
Files withMAYO FOUND MEDICAL EDUCATION & RES14BUCK INST RES AGING11UNITY BIOTECHNOLOGY INC6BUCK INSTITUTE FOR RES AND AGING1KIRKLAND JAMES L1
Top patents by PatentIndex Score
35 records- 0198US10010546B2Treatment of ophthalmic conditions by selectively removing senescent cells from the eyeBUCK INST RES AGING·Filed 2017·Granted Jul 3, 2018·23 cites·11 claims
- 0297US9968076B2Transgenic animals capable of being induced to delete senescent cellsMAYO FOUND MEDICAL EDUCATION & RES·Filed 2015·Granted May 15, 2018·19 cites·31 claims
- 0397US9849128B2Unit dose of a cis-imidazoline for treating an osteoarthritic joint by removing senescent cellsBUCK INST RES AGING·Filed 2017·Granted Dec 26, 2017·24 cites·15 claims
- 0496US9993472B2Treatment for osteoarthritis in a joint by administering a means for inhibiting MDM2BUCK INST RES AGING·Filed 2015·Granted Jun 12, 2018·20 cites·7 claims
- 0596US9980962B2Use of sulfonamide inhibitors of Bcl-2 to treat senescence-associated lung conditions such as pulmonary fibrosis and chronic obstructive pulmonary diseaseBUCK INST RES AGING·Filed 2017·Granted May 29, 2018·6 cites·8 claims
- 0696US9855266B2Treatment for osteoarthritis by intra-articular administration of a cis-imidazolineBUCK INST RES AGING·Filed 2017·Granted Jan 2, 2018·12 cites·14 claims
- 0795US10328073B2Use of sulfonamide inhibitors of BCL-2 and BCL-xL to treat ophthalmic disease by selectively removing senescent cellsUNITY BIOTECHNOLOGY INC·Filed 2018·Granted Jun 25, 2019·9 cites·16 claims
- 0895US10130628B2Treatment of joint painUNITY BIOTECHNOLOGY INC·Filed 2017·Granted Nov 20, 2018·6 cites·8 claims
- 0994US10478432B2Compositions of matter for treatment of ophthalmic conditions by selectively removing senescent cells from the eyeBUCK INST RES AGING·Filed 2018·Granted Nov 19, 2019·7 cites·18 claims
- 1092US10517866B2Removing senescent cells from a mixed cell population or tissue using a phosphoinositide 3-kinase (PI3K) inhibitorUNITY BIOTECHNOLOGY INC·Filed 2018·Granted Dec 31, 2019·5 cites·15 claims
- 1192US10258618B2Treating pulmonary conditions by selectively removing senescent cells from the lung using an intermittent dosing regimenBUCK INST RES AGING·Filed 2018·Granted Apr 16, 2019·5 cites·17 claims
- 1291US10328058B2Treating atherosclerosis by removing senescent foam cell macrophages from atherosclerotic plaquesMAYO FOUND MEDICAL EDUCATION & RES·Filed 2017·Granted Jun 25, 2019·5 cites·12 claims
- 1391US10213426B2Method of optimizing conditions for selectively removing a plurality of senescent cells from a tissue or a mixed cell populationBUCK INST RES AGING·Filed 2017·Granted Feb 26, 2019·5 cites·13 claims
- 1490US11351167B2Treating cognitive decline and other neurodegenerative conditions by selectively removing senescent cells from neurological tissueBUCK INST RES AGING·Filed 2019·Granted Jun 7, 2022·1 cites·14 claims
- 1590US10478433B2Unit dose of an aryl sulfonamide that is effective for treating eye disease and averting potential vision lossUNITY BIOTECHNOLOGY INC·Filed 2018·Granted Nov 19, 2019·4 cites·20 claims
- 1690US10413542B2Methods and compositions for killing senescent cells and for treating senescence-associated diseases and disorders using an inhibitor of Akt kinaseBUCK INST RES AGING·Filed 2018·Granted Sep 17, 2019·4 cites·12 claims
- 1782US11925640B2Methods and materials for improving arteriovenous fistula maturation and maintaining arteriovenous fistula functionalityMAYO FOUND MEDICAL EDUCATION & RES·Filed 2019·Granted Mar 12, 2024·1 cites·15 claims
- 1880US12226416B2Methods and materials for improving arteriovenous fistula maturation and maintaining arteriovenous fistula functionalityMAYO FOUND MEDICAL EDUCATION & RES·Filed 2024·Granted Feb 18, 2025·0 cites·16 claims
- 1979US11980616B2Treating liver disease by selectively eliminating senescent cellsBUCK INST RES AGING·Filed 2020·Granted May 14, 2024·0 cites·23 claims
- 2079US11517572B2Killing senescent cells and treating senescence-associated conditions using a SRC inhibitor and a flavonoidMAYO FOUND MEDICAL EDUCATION & RES·Filed 2020·Granted Dec 6, 2022·1 cites·3 claims
- 2179US2019343832A1Therapy for removing senescent cells and treating senescence-associated disease using an mdm2 inhibitorUNITY BIOTECHNOLOGY INC·Filed 2019·Application pending·0 cites
- 2269US2023218617A1Killing senescent cells and treating senescence-associated conditions using a src inhibitor and a flavonoidMAYO FOUND MEDICAL EDUCATION & RES·Filed 2022·Application pending·0 cites
- 2366US10251376B2Increasing healthy lifespan and delaying progression of age-related phenotypes by selectively removing senescent cellsMAYO FOUND MEDICAL EDUCATION & RES·Filed 2018·Granted Apr 9, 2019·0 cites·12 claims
- 2465US2018279590A1Nucleic Acid Construct Comprising a P16 Promoter Controlling Expression of a Transgene that Causes Apoptosis in Senescent CellsMAYO FOUND MEDICAL EDUCATION & RES·Filed 2018·Application pending·0 cites
- 2562US2019022225A1Protocol for increasing life expectancy in a test subjectMAYO FOUND MEDICAL EDUCATION & RES·Filed 2018·Application pending·0 cites
- 2662US2025170129A1Senotherapeutic agents and alpha-klotho polypeptidesMAYO FOUND FOR MEDICAL EDUCATION AND RESEARC·Filed 2023·Application pending·0 cites
- 2761US2022386574A1P21-cre animal modelsMAYO FOUND MEDICAL EDUCATION & RES·Filed 2022·Application pending·0 cites
- 2858US2014189897A1Transgenic animals capable of being induced to delete senescent cellsKIRKLAND JAMES L·Filed 2012·Application pending·0 cites
- 2958US2019269675A1Treatment of parkinson's disease and other conditions caused or mediated by senescent astrocytes using small molecule senolytic agentsBUCK INSTITUTE FOR RES AND AGING·Filed 2019·Application pending·0 cites
- 3056US2021379068A1Methods and materials for treating neuropsychiatric disordersMAYO FOUND MEDICAL EDUCATION & RES·Filed 2019·Application pending·0 cites
- 3152US2024016804A1Methods and materials for assessing and treating hypertensive disordersMAYO FOUND MEDICAL EDUCATION & RES·Filed 2020·Application pending·0 cites
- 3251US2017216286A1Killing senescent cells and treating senescence-associated conditions using a src inhibitor and a flavonoidMAYO FOUNDATION·Filed 2015·Application pending·0 cites
- 3351US2018193458A1Compositions and methods for treating senescence-associated diseases and disordersUNITY BIOTECHNOLOGY INC·Filed 2016·Application pending·0 cites
- 3450US2021283185A1Methods and materials for improving transplant outcomesMAYO FOUND MEDICAL EDUCATION & RES·Filed 2019·Application pending·0 cites
- 3549US2019000846A1Pharmaceutical Products and Drug Combinations for Treating Atherosclerosis by Stabilizing Atherosclerotic Plaques and Promoting Plaque RegressionMAYO FOUND MEDICAL EDUCATION & RES·Filed 2018·Application pending·0 cites
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