Inventor
HEARTLEIN MICHAEL
US155 patents
⚠️ This page may combine multiple inventors who share the name “HEARTLEIN MICHAEL”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.
TRANSLATE BIO INC
40 patentsUS10507249B2Dec 17, 2019
Lipid nanoparticle compositions and methods for mRNA delivery
TRANSLATE BIO INC19 citations98
US10413618B2Sep 17, 2019
Lipid nanoparticle compositions and methods for mRNA delivery
TRANSLATE BIO INC26 citations98
US10350303B1Jul 16, 2019
Lipid nanoparticle compositions and methods for mRNA delivery
TRANSLATE BIO INC24 citations98
US10238754B2Mar 26, 2019
Lipid nanoparticle compositions and methods for MRNA delivery
TRANSLATE BIO INC35 citations98
US9850269B2Dec 26, 2017
Methods for purification of messenger RNA
TRANSLATE BIO INC54 citations98
US9957499B2May 1, 2018
Methods for purification of messenger RNA
TRANSLATE BIO INC38 citations95
US11291734B2Apr 5, 2022
Lipid nanoparticle compositions and methods for mRNA delivery
TRANSLATE BIO INC10 citations94
US11059841B2Jul 13, 2021
Methods for purification of messenger RNA
TRANSLATE BIO INC16 citations94
US11052159B2Jul 6, 2021
Lipid nanoparticle compositions and methods for mRNA delivery
TRANSLATE BIO INC10 citations94
US10888626B2Jan 12, 2021
Lipid nanoparticle compositions and methods for mRNA delivery
TRANSLATE BIO INC13 citations94
US10471153B2Nov 12, 2019
Ice-based lipid nanoparticle formulation for delivery of mRNA
TRANSLATE BIO INC15 citations94
US10208295B2Feb 19, 2019
MRNA therapy for phenylketonuria
TRANSLATE BIO INC22 citations94
US10155785B2Dec 18, 2018
Methods for purification of messenger RNA
TRANSLATE BIO INC22 citations94
US10143758B2Dec 4, 2018
Liver specific delivery of messenger RNA
TRANSLATE BIO INC28 citations94
US10052284B2Aug 21, 2018
Lipid formulations for delivery of messenger RNA
TRANSLATE BIO INC20 citations94
US10022455B2Jul 17, 2018
Biodegradable lipids for delivery of nucleic acids
TRANSLATE BIO INC17 citations94
US9970047B2May 15, 2018
Quantitative assessment for cap efficiency of messenger RNA
TRANSLATE BIO INC17 citations94
US9877919B2Jan 30, 2018
Lipid-derived neutral nanoparticles
TRANSLATE BIO INC22 citations94
US11185595B2Nov 30, 2021
Lipid nanoparticle compositions and methods for mRNA delivery
TRANSLATE BIO INC7 citations93
US10137087B2Nov 27, 2018
Lipid-derived neutral nanoparticles
TRANSLATE BIO INC12 citations93
US9943595B2Apr 17, 2018
Messenger RNA therapy for treatment of articular disease
TRANSLATE BIO INC13 citations93
US10130649B2Nov 20, 2018
Synergistic enhancement of the delivery of nucleic acids via blended formulations
TRANSLATE BIO INC15 citations92
US10959953B2Mar 30, 2021
Lipid formulations for delivery of messenger RNA
TRANSLATE BIO INC10 citations85
US11820977B2Nov 21, 2023
Methods for purification of messenger RNA
TRANSLATE BIO INC3 citations84
US11692189B2Jul 4, 2023
Methods for purification of messenger RNA
TRANSLATE BIO INC3 citations84
US11547764B2Jan 10, 2023
Lipid nanoparticle compositions and methods for MRNA delivery
TRANSLATE BIO INC2 citations84
US11338044B2May 24, 2022
Lipid nanoparticle compositions and methods for mRNA delivery
TRANSLATE BIO INC5 citations84
US10975369B2Apr 13, 2021
Methods for purification of messenger RNA
TRANSLATE BIO INC7 citations84
US10940207B2Mar 9, 2021
Ice-based lipid nanoparticle formulation for delivery of mRNA
TRANSLATE BIO INC4 citations84
US10876104B2Dec 29, 2020
Methods for purification of messenger RNA
TRANSLATE BIO INC6 citations84
US10822368B2Nov 3, 2020
Ribonucleic acids with 4′-thio-modified nucleotides and related methods
TRANSLATE BIO INC6 citations84
US10808241B2Oct 20, 2020
Methods for purification of messenger RNA
TRANSLATE BIO INC9 citations84
US10786455B2Sep 29, 2020
Lipid-derived neutral nanoparticles
TRANSLATE BIO INC5 citations84
US10766852B2Sep 8, 2020
Ionizable cationic lipids
TRANSLATE BIO INC5 citations84
US10646504B2May 12, 2020
Synergistic enhancement of the delivery of nucleic acids via blended formulations
TRANSLATE BIO INC8 citations84
US10626439B2Apr 21, 2020
Quantitative assessment for cap efficiency of messenger RNA
TRANSLATE BIO INC4 citations84
US10493031B2Dec 3, 2019
Lipid formulations for delivery of messenger RNA
TRANSLATE BIO INC7 citations84
US10493166B2Dec 3, 2019
Biodegradable lipids for delivery of nucleic acids
TRANSLATE BIO INC5 citations84
US10428349B2Oct 1, 2019
Multimeric coding nucleic acid and uses thereof
TRANSLATE BIO INC4 citations84
US10293057B2May 21, 2019
Biodegradable lipids for delivery of nucleic acids
TRANSLATE BIO INC5 citations84
SHIRE HUMAN GENETIC THERAPIES
8 patentsUS9522176B2Dec 20, 2016
MRNA therapy for phenylketonuria
SHIRE HUMAN GENETIC THERAPIES38 citations98
US9308281B2Apr 12, 2016
MRNA therapy for Fabry disease
SHIRE HUMAN GENETIC THERAPIES40 citations98
US9061021B2Jun 23, 2015
mRNA for use in treatment of human genetic diseases
SHIRE HUMAN GENETIC THERAPIES43 citations98
US9629804B2Apr 25, 2017
Lipid formulations for delivery of messenger RNA
SHIRE HUMAN GENETIC THERAPIES60 citations97
US9181321B2Nov 10, 2015
CFTR mRNA compositions and related methods and uses
SHIRE HUMAN GENETIC THERAPIES50 citations97
US9597413B2Mar 21, 2017
Pulmonary delivery of mRNA
SHIRE HUMAN GENETIC THERAPIES17 citations96
US9713626B2Jul 25, 2017
CFTR mRNA compositions and related methods and uses
SHIRE HUMAN GENETIC THERAPIES23 citations94
US9546128B2Jan 17, 2017
Ionizable cationic lipids
SHIRE HUMAN GENETIC THERAPIES12 citations93
GUILD BRAYDON CHARLES
2 patentsShowing the top 50 of 155 patents by PatentIndex Score.