Inventor · disambiguated record
Daniel L. Comins
Also filed as: COMINS DANIEL · COMINS DANIEL L
43 granted patents·2 pending applications·412 citations·filing 1990–2022
98Inventor score
Files withUNIV NORTH CAROLINA STATE35OSI PHARM INC3COMINS DANIEL L2ROYAL CARIBBEAN CRUISES LTD2GLAXO WELLCOME INC1
Top patents by PatentIndex Score
45 records- 0195US6995265B2Synthesis of nicotine derivatives from nicotineUNIV NORTH CAROLINA STATE·Filed 2004·Granted Feb 7, 2006·36 cites·19 claims
- 0294US6063923APreparation of a camptothecin derivative by intramolecular cyclisationGLAXO WELLCOME INC·Filed 1995·Granted May 16, 2000·62 cites·26 claims
- 0393US7132545B2Synthesis of nicotine derivatives from nicotineUNIV NORTH CAROLINA STATE·Filed 2005·Granted Nov 7, 2006·9 cites·5 claims
- 0493US5162532AIntermediates and method of making camptothecin and camptothecin analogsUNIV NORTH CAROLINA STATE·Filed 1990·Granted Nov 10, 1992·54 cites·21 claims
- 0588US5321140APyridinecarboxaldehyde D-ring intermediates useful for the synthesis of camptothecin and camptothecin analogsUNIV NORTH CAROLINA STATE·Filed 1993·Granted Jun 14, 1994·28 cites·9 claims
- 0688US5191082ACamptothecin intermediate and method of making camptothecin intermediatesUNIV NORTH CAROLINA STATE·Filed 1992·Granted Mar 2, 1993·34 cites·5 claims
- 0786US5200524ACamptothecin intermediates and method of making sameUNIV NORTH CAROLINA STATE·Filed 1992·Granted Apr 6, 1993·29 cites·7 claims
- 0885US7304160B2Regiospecific synthesis of nicotine derivativesUNIV NORTH CAROLINA STATE·Filed 2006·Granted Dec 4, 2007·4 cites·5 claims
- 0985US5247089AMethod of making intermediates useful for the manufacture of camptothecin and camptothecin analogsUNIV NORTH CAROLINA STATE·Filed 1992·Granted Sep 21, 1993·28 cites·22 claims
- 1083US7179917B2Regioselective halogenation of nicotine and substituted nicotinesUNIV NORTH CAROLINA STATE·Filed 2006·Granted Feb 20, 2007·4 cites·6 claims
- 1183US5243050AAlkylpyridone DE ring intermediates useful for the manufacture of camptothecin and camptothecin analogsUNIV NORTH CAROLINA STATE·Filed 1992·Granted Sep 7, 1993·22 cites·12 claims
- 1280US7361768B2Synthesis of nicotine derivatives from nicotineUNIV NORTH CAROLINA STATE·Filed 2006·Granted Apr 22, 2008·2 cites·5 claims
- 1378US7501520B2Regioselective halogenation of nicotine and substituted nicotinesNORTH CARLINA STATE UNIVERSITY·Filed 2007·Granted Mar 10, 2009·4 cites·15 claims
- 1477US5459269A14-halo-camptothecinsUNIV NORTH CAROLINA STATE·Filed 1994·Granted Oct 17, 1995·17 cites·8 claims
- 1576US11433417B2Water-based pyrotechnic illusionROYAL CARIBBEAN CRUISES LTD·Filed 2020·Granted Sep 6, 2022·1 cites·29 claims
- 1676US7067672B2Regioselective halogenation of nicotine and substituted nicotinesUNIV NORTH CAROLINA STATE·Filed 2004·Granted Jun 27, 2006·7 cites·9 claims
- 1774US11819865B2Water-based pyrotechnic illusionROYAL CARIBBEAN CRUISES LTD·Filed 2022·Granted Nov 21, 2023·0 cites·31 claims
- 1874US5212317AMethods and intermediates for the assymmetric synthesis of camptothecin and camptothecin analogsUNIV NORTH CAROLINA STATE·Filed 1992·Granted May 18, 1993·14 cites·51 claims
- 1972US7888512B2Synthesis of nicotine derivatives from nicotineUNIV NORTH CAROLINA STATE·Filed 2009·Granted Feb 15, 2011·0 cites·16 claims
- 2069US7112678B2Regiospecific synthesis of nicotine derivativesUNIV NORTH CAROLINA STATE·Filed 2003·Granted Sep 26, 2006·3 cites·10 claims
- 2169US5475108ACamptothecin intermediates and method of making camptothecin and comptothecin analogsUNIV NORTH CAROLINA STATE·Filed 1993·Granted Dec 12, 1995·9 cites·7 claims
- 2265US5315007AProcess for making DE ring intermediates for the synthesis of camptothecin and camptothecin analogsUNIV NORTH CAROLINA STATE·Filed 1993·Granted May 24, 1994·8 cites·12 claims
- 2364US7671209B2Regiospecific synthesis of nicotine derivativesUNIV NORTH CAROLINA STATE·Filed 2007·Granted Mar 2, 2010·0 cites·20 claims
- 2463US5258516AOptically pure D,E ring intermediates useful for the synthesis of camptothecin and camptothecin analogsNC STATE UNIVERSITY·Filed 1993·Granted Nov 2, 1993·9 cites·6 claims
- 2562US7553968B2Synthesis of nicotine derivatives from nicotineUNIV NORTH CAROLINA STATE·Filed 2008·Granted Jun 30, 2009·0 cites·10 claims
- 2662US6462196B1Preparation of a camptothecin derivative by intramolecular cyclizationOSI PHARM INC·Filed 2000·Granted Oct 8, 2002·1 cites·2 claims
- 2761US5264579AD ring intermediates for the synthesis of camptothecin and camptothecin analogsUNIV NORTH CAROLINA STATE·Filed 1993·Granted Nov 23, 1993·6 cites·15 claims
- 2859US7820826B2Synthesis and regioselective substitution of 6-halo-and 6-alkoxy nicotine derivativesUNIV NORTH CAROLINA STATE·Filed 2007·Granted Oct 26, 2010·0 cites·22 claims
- 2958US5395939AMethod of making asymmetric de ring intermediates for the synthesis of camptothecin and camptothecin analogsUNIV NORTH CAROLINA STATE·Filed 1993·Granted Mar 7, 1995·4 cites·7 claims
- 3057US6987189B2Short synthesis of pyridine-based pharmaceutical intermediatesUNIV NORTH CAROLINA STATE·Filed 2004·Granted Jan 17, 2006·0 cites·8 claims
- 3155US7875724B2Regiospecific synthesis of nicotine derivativesUNIV NORTH CAROLINA STATE·Filed 2010·Granted Jan 25, 2011·0 cites·4 claims
- 3255US6855825B2Short synthesis of pyridine-based pharmaceutical intermediatesUNIV NORTH CAROLINA STATE·Filed 2003·Granted Feb 15, 2005·0 cites·6 claims
- 3354US5428166AMethod of making asymmetric de ring intermediates for the synthesis of camptothecin and camptothecin analogsUNIV NORTH CAROLINA STATE·Filed 1994·Granted Jun 27, 1995·4 cites·26 claims
- 3453US6706884B2Short synthesis of pyridine-based pharmaceutical intermediatesUNIV NORTH CAROLINA STATE·Filed 2002·Granted Mar 16, 2004·0 cites·5 claims
- 3553US2013131015A1Synthesis and regioselective substitution of 6-halo- and 6-alkoxy nicotine derivativesUNIV NORTH CAROLINA STATE·Filed 2013·Application pending·0 cites
- 3651US6821982B2Preparation of a camptothecin derivative by intramolecular cyclisationOSI PHARM INC·Filed 2003·Granted Nov 23, 2004·0 cites·5 claims
- 3750US6559309B2Preparation of a camptothecin derivative by intramolecular cyclisationOSI PHARM INC·Filed 2002·Granted May 6, 2003·0 cites·18 claims
- 3850US6534656B2Short synthesis of pyridine-based pharmaceutical intermediatesUNIV NORTH CAROLINA STATE·Filed 2001·Granted Mar 18, 2003·0 cites·7 claims
- 3950US2011251390A1Nicotine-based compounds useful for asymmetric synthesisCOMINS DANIEL L·Filed 2009·Application pending·0 cites
- 4044US5262571ACycloalkyl-based chiral auxiliaries and method making the sameUNIV NORTH CAROLINA STATE·Filed 1992·Granted Nov 16, 1993·4 cites·15 claims
- 4143US5496952AMethod of making asymmetric DE ring intermediates for the synthesis of camptothecin and camptothecin analogsUNIV NORTH CAROLINA STATE·Filed 1995·Granted Mar 5, 1996·2 cites·22 claims
- 4242US8389732B2Synthesis and regioselective substitution of 6-halo- and 6-alkoxy nicotine derivativesCOMINS DANIEL L·Filed 2010·Granted Mar 5, 2013·0 cites·21 claims
- 4339US5478943AMethod of making intermediates for camptothecin and its analogsUNIV NORTH CAROLINA STATE·Filed 1995·Granted Dec 26, 1995·1 cites·7 claims
- 4439US5254690AAlkoxymethylpyridine d-ring intermediates useful for the synthesis of camptpthecin and camptothecin analogsUNIV NORTH CAROLINA STATE·Filed 1993·Granted Oct 19, 1993·6 cites·7 claims
- 4536US5486615AMethod of making asymmetric DE ring intermediates for the synthesis of camptothecin analogsUNIV NORTH CAROLINA STATE·Filed 1994·Granted Jan 23, 1996·0 cites·7 claims
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