Inventor · disambiguated record
David H. Gelfand
Also filed as: GELFAND DAVID · GELFAND DAVID H · GELFAND DAVID HARROW
67 granted patents·7 pending applications·15,306 citations·filing 1983–2017
99Inventor score
Files withROCHE MOLECULAR SYSTEMS INC26HOFFMANN LA ROCHE19CETUS CORP14GELFAND DAVID H5BAUER KEITH A4
Top patents by PatentIndex Score
74 records- 0199US5310652AReverse transcription with thermostable DNA polymerase-high temperature reverse transcriptionHOFFMANN LA ROCHE·Filed 1993·Granted May 10, 1994·386 cites·7 claims
- 0299US4965188AProcess for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzymeCETUS CORP·Filed 1987·Granted Oct 23, 1990·4k cites·50 claims
- 0398US7445900B2Homogeneous assay systemROCHE MOLECULAR SYSTEMS INC·Filed 2005·Granted Nov 4, 2008·56 cites·6 claims
- 0498US7141377B2Process for discrimination of nucleic acid sequence variantsROCHE MOLECULAR SYSTEMS INC·Filed 2005·Granted Nov 28, 2006·81 cites·21 claims
- 0598US6127155AStabilized thermostable nucleic acid polymerase compositions containing non-ionic polymeric detergentsROCHE MOLECULAR SYSTEMS INC·Filed 1992·Granted Oct 3, 2000·182 cites·18 claims
- 0698US5804375AReaction mixtures for detection of target nucleic acidsROCHE MOLECULAR SYSTEMS INC·Filed 1995·Granted Sep 8, 1998·585 cites·24 claims
- 0798US5487972ANucleic acid detection by the 5'-3'exonuclease activity of polymerases acting on adjacently hybridized oligonucleotidesHOFFMANN LA ROCHE·Filed 1993·Granted Jan 30, 1996·855 cites·32 claims
- 0898US5210015AHomogeneous assay system using the nuclease activity of a nucleic acid polymeraseHOFFMANN LA ROCHE·Filed 1990·Granted May 11, 1993·2.1k cites·38 claims
- 0998US4889818APurified thermostable enzymeCETUS CORP·Filed 1987·Granted Dec 26, 1989·1.2k cites·3 claims
- 1097US5618711ARecombinant expression vectors and purification methods for Thermus thermophilus DNA polymeraseHOFFMANN LA ROCHE·Filed 1995·Granted Apr 8, 1997·301 cites·11 claims
- 1196US6214979B1Homogeneous assay systemROCHE MOLECULAR SYSTEMS·Filed 1997·Granted Apr 10, 2001·209 cites·4 claims
- 1296US5374553ADNA encoding a thermostable nucleic acid polymerase enzyme from thermotoga maritimaHOFFMANN LA ROCHE·Filed 1990·Granted Dec 20, 1994·306 cites·8 claims
- 1396US5079352APurified thermostable enzymeCETUS CORP·Filed 1990·Granted Jan 7, 1992·555 cites·27 claims
- 1495US6514736B1Kits for amplifying and detecting nucleic acid sequencesROCHE MOLECULAR SYSTEMS INC·Filed 2000·Granted Feb 4, 2003·71 cites·9 claims
- 1595US5418149AReduction of non-specific amplification glycosylase using DUTP and DNA uracilHOFFMANN LA ROCHE·Filed 1991·Granted May 23, 1995·399 cites·4 claims
- 1695US5322770AReverse transcription with thermostable DNA polymerases - high temperature reverse transcriptionHOFFMAN LAROCHE INC·Filed 1989·Granted Jun 21, 1994·576 cites·18 claims
- 1794US7745125B22′-terminator related pyrophosphorolysis activated polymerizationROCHE MOLECULAR SYSTEMS INC·Filed 2006·Granted Jun 29, 2010·24 cites·32 claims
- 1894US6197563B1Kits for amplifying and detecting nucleic acid sequencesROCHE MOLECULAR SYSTEMS INC·Filed 1994·Granted Mar 6, 2001·141 cites·18 claims
- 1994US5674738ADNA encoding thermostable nucleic acid polymerase enzyme from thermus species Z05ROCHE MOLECULAR SYSTEMS INC·Filed 1995·Granted Oct 7, 1997·181 cites·17 claims
- 2093US7572581B22′-terminator nucleotide-related methods and systemsROCHE MOLECULAR SYSTEMS INC·Filed 2004·Granted Aug 11, 2009·41 cites·52 claims
- 2193US6040166AKits for amplifying and detecting nucleic acid sequences, including a probeROCHE MOLECULAR SYSTEMS INC·Filed 1994·Granted Mar 21, 2000·178 cites·7 claims
- 2293US5789224ARecombinant expression vectors and purification methods for thermus thermophilus DNA polymeraseROCHE MOLECULAR SYSTEMS INC·Filed 1995·Granted Aug 4, 1998·139 cites·5 claims
- 2393US5624833APurified thermostable nucleic acid polymerase enzyme from Thermotoga maritimaHOFFMANN LA ROCHE·Filed 1995·Granted Apr 29, 1997·119 cites·12 claims
- 2492US5561058AMethods for coupled high temperatures reverse transcription and polymerase chain reactionsHOFFMANN LA ROCHE·Filed 1995·Granted Oct 1, 1996·170 cites·22 claims
- 2592US5466591A5' to 3' exonuclease mutations of thermostable DNA polymerasesHOFFMANN LA ROCHE·Filed 1991·Granted Nov 14, 1995·229 cites·4 claims
- 2692US4711845APortable temperature-sensitive control cassetteCETUS CORP·Filed 1984·Granted Dec 8, 1987·80 cites·26 claims
- 2791US5693517AReagents and methods for coupled high temperature reverse transcription and polymerase chain reactionsROCHE MOLECULAR SYSTEMS INC·Filed 1995·Granted Dec 2, 1997·135 cites·6 claims
- 2891US5618703AUnconventional nucleotide substitution in temperature selective RT-PCRHOFFMANN LA ROCHE·Filed 1994·Granted Apr 8, 1997·122 cites·7 claims
- 2991US5407800AReverse transcription with Thermus thermophilus polymeraseHOFFMANN LA ROCHE·Filed 1993·Granted Apr 18, 1995·167 cites·17 claims
- 3090US5641864AKits for high temperature reverse transcription of RNAHOFFMANN LA ROCHE·Filed 1994·Granted Jun 24, 1997·139 cites·18 claims
- 3189US9102924B2DNA polymerases and related methodsBAUER KEITH A·Filed 2009·Granted Aug 11, 2015·12 cites·30 claims
- 3289US6346379B1Thermostable DNA polymerases incorporating nucleoside triphosphates labeled with fluorescein family dyesHOFFMANN LA ROCHE·Filed 1998·Granted Feb 12, 2002·87 cites·38 claims
- 3389US5939292AThermostable DNA polymerases having reduced discrimination against ribo-NTPsROCHE MOLECULAR SYSTEMS INC·Filed 1997·Granted Aug 17, 1999·108 cites·25 claims
- 3488US8962293B2DNA polymerases and related methodsBAUER KEITH A·Filed 2007·Granted Feb 24, 2015·7 cites·22 claims
- 3588US5795762A5' to 3' exonuclease mutations of thermostable DNA polymerasesROCHE MOLECULAR SYSTEMS INC·Filed 1995·Granted Aug 18, 1998·96 cites·13 claims
- 3688US5075216AMethods for dna sequencing with thermus aquaticus dna polymeraseCETUS CORP·Filed 1988·Granted Dec 24, 1991·260 cites·31 claims
- 3788US4784949AUniversal dominant selectable marker cassetteCETUS CORP·Filed 1984·Granted Nov 15, 1988·53 cites·29 claims
- 3887US6228628B1Mutant chimeric DNA polymeraseROCHE MOLECULAR SYSTEMS·Filed 1998·Granted May 8, 2001·130 cites·63 claims
- 3987US5455170AMutated thermostable nucleic acid polymerase enzyme from Thermus species Z05HOFFMANN LA ROCHE·Filed 1993·Granted Oct 3, 1995·136 cites·9 claims
- 4086US7148049B2Thermostable or thermoactive DNA polymerase molecules with attenuated 3′-5′ exonuclease activityROCHE MOLECULAR SYSTEMS INC·Filed 2003·Granted Dec 12, 2006·13 cites·3 claims
- 4186US5420029AMutated thermostable nucleic acid polymerase enzyme from thermotoga maritimaHOFFMANN LA ROCHE·Filed 1991·Granted May 30, 1995·95 cites·17 claims
- 4286US5352600APurified thermostable enzymeHOFFMANN LA ROCHE·Filed 1992·Granted Oct 4, 1994·97 cites·4 claims
- 4385US9738876B2DNA polymerases and related methodsROCHE MOLECULAR SYSTEMS INC·Filed 2015·Granted Aug 22, 2017·2 cites·22 claims
- 4484US8071536B2Mutant DNA polymerases with improved pyrophosphorolysis activated polymerization (PAP) abilityBAUER KEITH A·Filed 2008·Granted Dec 6, 2011·5 cites·22 claims
- 4584US7919249B22′-Terminator nucleotide-related methods and systemsROCHE MOLECULAR SYSTEMS INC·Filed 2008·Granted Apr 5, 2011·5 cites·52 claims
- 4684US5491086APurified thermostable nucleic acid polymerase and DNA coding sequences from pyrodictium speciesHOFFMANN LA ROCHE·Filed 1993·Granted Feb 13, 1996·72 cites·20 claims
- 4783US7179590B2High temperature reverse transcription using mutant DNA polymerasesROCHE MOLECULAR SYSTEMS INC·Filed 2001·Granted Feb 20, 2007·19 cites·29 claims
- 4883US5405774ADNA encoding a mutated thermostable nucleic acid polymerase enzyme from thermus species sps17HOFFMANN LA ROCHE·Filed 1993·Granted Apr 11, 1995·98 cites·11 claims
- 4982US4666848APolypeptide expression using a portable temperature sensitive control cassette with a positive retroregulatory elementCETUS CORP·Filed 1984·Granted May 19, 1987·44 cites·17 claims
- 5080US5968799APurified thermostable nucleic acid polymerase enzyme from thermosipho africanusROCHE MOLECULAR SYSTEMS INC·Filed 1991·Granted Oct 19, 1999·60 cites·2 claims
Showing the top 50 of 74 patent records by PatentIndex Score.
Identity basis: PatentsView inventor disambiguation (2025Q4-odp release). How scoring works →