Inventor · disambiguated record
David L. Coffen
Also filed as: COFFEN CHARLOTTE · COFFEN DAVID · COFFEN DAVID L · COFFEN DAVID LLEWELLYN
34 granted patents·5 pending applications·195 citations·filing 1974–2012
97Inventor score
Top patents by PatentIndex Score
39 records- 0194US7763747B2Compounds, compositions and methods for the treatment of amyloid diseases and synucleinopathies such as alzheimer's disease, type 2 diabetes, and parkinson's diseasePROTEOTECH INC·Filed 2008·Granted Jul 27, 2010·21 cites·21 claims
- 0288US7514583B2Compounds, compositions and methods for the treatment of amyloid diseases and synucleinopathies such as alzheimer's disease, type 2 diabetes, and parkinson's diseasePROTEOTECH INC·Filed 2003·Granted Apr 7, 2009·22 cites·22 claims
- 0388US4093654AProduction of pyridoxine intermediates from diketeneHOFFMANN LA ROCHE·Filed 1977·Granted Jun 6, 1978·15 cites·2 claims
- 0487US7601876B2Compounds, compositions and methods for the treatment of amyloid diseases such as systemic AA amyloidosisPROTEOTECH INC·Filed 2007·Granted Oct 13, 2009·8 cites·36 claims
- 0587US4026901AConversion of 4-lower alkyloxazole-5-carboxamide to 4-lower alkyl-5-cyanooxazolesHOFFMANN LA ROCHE·Filed 1975·Granted May 31, 1977·15 cites·9 claims
- 0683US6355641B1Oxazolone derivatives and uses thereofSYNTEX LLC·Filed 2000·Granted Mar 12, 2002·14 cites·30 claims
- 0776US8163957B2Compounds, compositions and methods for the treatment of amyloid diseases and synucleinopathies such as alzheimer's disease, type 2 diabetes and parkinson's diseaseSNOW ALAN D·Filed 2010·Granted Apr 24, 2012·2 cites·22 claims
- 0875US6452050B1Synthesis and use of α-ketoamide derivatives and arraysARQULE INC·Filed 2000·Granted Sep 17, 2002·7 cites·11 claims
- 0974US8586585B2Compounds, compositions and methods for the treatment of amyloid diseases and synucleinopathies such as Alzheimer's disease, type 2 diabetes and Parkinson's diseaseSNOW ALAN D·Filed 2012·Granted Nov 19, 2013·1 cites·4 claims
- 1071US5008411AGlycidic acid ester and process of preparationHOFFMANN LA ROCHE·Filed 1989·Granted Apr 16, 1991·11 cites·5 claims
- 1170US6143931ASynthesis and use of α-ketoamide derivatives and arraysARQULE INC·Filed 1998·Granted Nov 7, 2000·12 cites·24 claims
- 1269US6358750B1Spiro[pyrrolidine-2,3′-oxindole] compounds and method of useARQULE INC·Filed 2000·Granted Mar 19, 2002·4 cites·13 claims
- 1368US5061629AProduction of 2-hydroxy substituted arylalkanoic acids and esters by enzymatic hydrolysisHOFFMANN LA ROCHE·Filed 1990·Granted Oct 29, 1991·14 cites·8 claims
- 1466US4214002APreservation of aqueous systems with 2-chloro-3-oxobutyramide derivativesGIVAUDAN CORP·Filed 1978·Granted Jul 22, 1980·5 cites·22 claims
- 1565US6114540ASpiro[pyrrolidine-2,3'-oxindole] compounds and methods of useARQULE INC·Filed 1998·Granted Sep 5, 2000·10 cites·24 claims
- 1665US2009197965A1Compounds, compositions and methods for the treatment of amyloid diseases and synucleinopathies such as alzheimer's disease, type 2 diabetes, and parkinson's diseaseSNOW ALAN D·Filed 2008·Application pending·0 cites
- 1759US4118587ANovel 4-phenoxy-5-sulfamylbenzoic acid derivativesHOFFMANN LA ROCHE·Filed 1976·Granted Oct 3, 1978·3 cites·4 claims
- 1857US4789750A2-(trimethyl-tridecenyl)-tetramethylchroman intermediates for vitamin EHOFFMANN LA ROCHE·Filed 1987·Granted Dec 6, 1988·5 cites·16 claims
- 1952US5037747AProduction of benzopyran-2-carboxylic acids and esters by enzymatic hydrolysisHOFFMANN LA ROCHE·Filed 1988·Granted Aug 6, 1991·6 cites·13 claims
- 2052US4193928ALasalocid derivativesHOFFMANN LA ROCHE·Filed 1978·Granted Mar 18, 1980·3 cites·13 claims
- 2149US4853472AVitamin E intermediatesHOFFMANN LA ROCHE·Filed 1988·Granted Aug 1, 1989·3 cites·3 claims
- 2248US4495354AProcess for bicyclic diketonesHOFFMANN LA ROCHE·Filed 1982·Granted Jan 22, 1985·2 cites·3 claims
- 2348US2002098598A1Method for tracking compounds in solution phase combinatorial chemistryFiled 2002·Application pending·0 cites
- 2447US4879395AVitamin E intermediateHOFFMANN LA ROCHE·Filed 1988·Granted Nov 7, 1989·2 cites·2 claims
- 2543US4199600APreservation of aqueous systems with α-halo-β-aminocrotonic acid estersGIVAUDAN CORP·Filed 1978·Granted Apr 22, 1980·4 cites·11 claims
- 2642US3932399A2,5-Epithio-1,4-benzodiazepinesHOFFMANN LA ROCHE·Filed 1974·Granted Jan 13, 1976·1 cites·3 claims
- 2742US2002068367A1Linker and method for solid phase combinatorial synthesisFiled 2001·Application pending·0 cites
- 2840US4882441ALower-alkyl or aryl-sulfonyl unsaturated tacopherolsHOFFMANN LA ROCHE·Filed 1988·Granted Nov 21, 1989·1 cites·5 claims
- 2937US4208535ANovel 4-phenoxy-5-sulfamylbenzoic acidHOFFMANN LA ROCHE·Filed 1978·Granted Jun 17, 1980·0 cites·2 claims
- 3037US2011104055A1Substituted n-aryl benzamides and related compounds for treatment of amyloid diseases and synucleinopathiesSNOW ALAN·Filed 2010·Application pending·0 cites
- 3136US4558140ACyclopenta[b]furan-2-onesHOFFMANN LA ROCHE·Filed 1984·Granted Dec 10, 1985·0 cites·9 claims
- 3235US4866205AProstaglandin intermediatesHOFFMANN LA ROCHE·Filed 1988·Granted Sep 12, 1989·0 cites·6 claims
- 3335US4247712APreservation of aqueous systems with 2-chloro-3-oxobutyramide derivativesGIVAUDAN CORP·Filed 1979·Granted Jan 27, 1981·0 cites·5 claims
- 3434US4707555AProstaglandin intermediatesHOFFMANN LA ROCHE·Filed 1985·Granted Nov 17, 1987·0 cites·2 claims
- 3534US4247690ALasalocid derivativesHOFFMANN LA ROCHE·Filed 1979·Granted Jan 27, 1981·0 cites·1 claims
- 3634US4217363APreservation of aqueous systems with α-chloro-β-aminocrotonamideGIVAUDAN CORP·Filed 1978·Granted Aug 12, 1980·1 cites·9 claims
- 3733US4483990APreparation of diketonesHOFFMANN LA ROCHE·Filed 1982·Granted Nov 20, 1984·0 cites·3 claims
- 3833US4206229APreservation of aqueous systems with α-bromo-β-aminocrotononitrileGIVAUDAN CORP·Filed 1978·Granted Jun 3, 1980·3 cites·6 claims
- 3933US2002052295A1Diacyl derivatives of propylene diamine having herbicidal activityFiled 2000·Application pending·0 cites
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