Inventor

MANOHARAN MUTHIAH

US326 patents

⚠️ This page may combine multiple inventors who share the name “MANOHARAN MUTHIAH”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.

MANOHARAN MUTHIAH

ISIS PHARMACEUTICALS INC

Oligonucleolotides having site specific chiral phosphorothioate internucleoside linkages

Amine-derivatized nucleosides and oligonucleosides

Amine-derivatized nucleosides and oligonucleosides

Peptide-conjugated oligomeric compounds

Gapped oligomers having site specific chiral phosphorothioate internucleoside linkages

Amine-derivatized nucleosides and oligonucleosides

Ligand-conjugated oligomeric compounds

Targeted oligonucleotide conjugates

Oligonucleotides conjugated to protein-binding drugs

Aminooxy-modified nucleosidic compounds and oligomeric compounds prepared therefrom

2′-O-aminoethyloxyethyl-modified oligonucleotides

Process for preparing peptide derivatized oligomeric compounds

Guanidinium functionalized oligonucleotides and method/synthesis

Oligonucleotide-folate conjugates

Targeted Oligonucleotide conjugates

Derivatized oligonucleotides having improved uptake and other properties

Nucleosidic and non-nucleosidic folate conjugates

Methods for the preparation of conjugated oligomers

Targeted oligonucleotide conjugates

Phosphorothioate oligonucleotides having modified internucleoside linkages

Methods of synthesis and use

Aminooxy-modified oligonucleotides and methods for making same

N-2 substituted purines

Preparation of phosphorothioate and boranophosphate oligomers

Derivatized oligonucleotides having improved uptake and other properties

2&#39;-O-aminooxy-modified oligonucleotides

N-2 substituted purines in oligonucleotides

Substituted purines and oligonucleotide cross-linking

Oligonucleotides containing N-2 substituted purines

Thiol-derivatized nucleosides

N-2 substituted purines

ALNYLAM PHARMACEUTICALS INC

Modified RNAi agents

Carbohydrate conjugates as delivery agents for oligonucleotides

Modified iRNA agents

Modified iRNA agents

Chemically modified oligonucleotides

Biodegradable lipids for the delivery of active agents

Biodegradable lipids for the delivery of active agents

RNAi agents, compositions and methods of use thereof for treating transthyretin (TTR) associated diseases

MANOHARAN MUTHIAH

Lipids and compositions for the delivery of therapeutics

Lipids and compositions for the delivery of therapeutics

5′ phosphate mimics

Lipid compositions

Lipid containing formulations

Carbohydrate conjugates as delivery agents for oligonucleotides

Therapeutic compositions

Carbohydrate conjugates as delivery agents for oligonucleotides

TEKMIRA PHARMACEUTICALS CORP

Site specific delivery of nucleic acids by combining targeting ligands with endosomolytic components

ALNYLAM PHARMACEUTICALS

IRNA agents with biocleavable tethers

ARBUTUS BIOPHARMA CORP

Lipids and compositions for the delivery of therapeutics

2'-O-aminooxy-modified oligonucleotides